"Of these uncharacterized proteins, 17 were tagged and localized in transfected mitotic cells, resulting in the identification of six genuine spindle components (KIAA0008, CdcA8, KIAA1187, FLJ12649, FLJ90806, and C20Orf129)"

"Large-scale mapping of human protein-protein interactions by mass spectrometry"

"Combined data from multiple biological replicates provided a dataset of 418 non-redundant proteins, 389 of which are putative novel interactors"

"a major category of c-Myc interactors were transcription factors and chromatin-associated proteins... actins, lamins and tubulins... numerous cytoskeleton associated proteins"

"This analysis is highly consistent with c-Myc being predominantly a nuclear protein that interacts with numerous proteins involved with transcription and chromatin organization"

"MAP7 family proteins (including MAP7D1) bind microtubules via an N-terminal MT-binding domain and bind kinesin-1 via a C-terminal domain"

"MAP7-family proteins bind the kinesin-1 stalk via a C-terminal domain"

"purified-protein reconstitution showed that MAP7 family proteins increase kinesin-1 microtubule landing rate and processivity"

"In HeLa cells, at least one MAP7-family member (including MAP7D1) is necessary and sufficient to enable kinesin-1-driven transport"

"Map7 / Map7D1 bind Dishevelled (Dvl) and form an interdependent feedback loop that directs cortical Dvl localization"

"Wnt5a signaling and kinesin-1 (KIF5B) activity promote MAP7/7D1 movement toward microtubule plus ends"

"MAP7D1 is required for maintenance of acetylated/stable microtubules"

"loss of Map7D1 reduces MT stability and alters cell migration and neurite outgrowth"

"MAP7D1 was shown to be specifically required for maintaining acetylated, stable microtubules, distinguishing its mechanism from MAP7D2"