GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000024
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
GO_REF:0000117
Electronic Gene Ontology annotations created by ARBA machine learning models
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
PMID:11940529
Contribution of Na(+)-K(+)-Cl(-) cotransporter to high-[K(+)](o)- induced swelling and EAA release in astrocytes.
PMID:12740379
PASK (proline-alanine-rich STE20-related kinase), a regulatory kinase of the Na-K-Cl cotransporter (NKCC1).
PMID:12946942
Ammonium effects on colonic Cl- secretion: anomalous mole fraction behavior.
PMID:15347682
Characterization of a novel interaction between the secretory Na+-K+-Cl- cotransporter and the chaperone hsp90.
PMID:16227993
NKCC1 transporter facilitates seizures in the developing brain.
PMID:16669787
Functional interactions of the SPAK/OSR1 kinases with their upstream activator WNK1 and downstream substrate NKCC1.
PMID:17478539
Dynamic and differential regulation of NKCC1 by calcium and cAMP in the native human colonic epithelium.
PMID:17721439
Structural insights into the recognition of substrates and activators by the OSR1 kinase.
PMID:18032481
Ammonium transport in the colonic crypt cell line, T84: role for Rhesus glycoproteins and NKCC1.
PMID:19199708
Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
PMID:20458337
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
PMID:21423148
MO25 is a master regulator of SPAK/OSR1 and MST3/MST4/YSK1 protein kinases.
PMID:22570591
Regulation of brain tumor dispersal by NKCC1 through a novel role in focal adhesion regulation.
PMID:24555568
WNK1-OSR1 kinase-mediated phospho-activation of Na+-K+-2Cl- cotransporter facilitates glioma migration.
PMID:24769233
Proteomic analysis of cerebrospinal fluid extracellular vesicles: a comprehensive dataset.
PMID:27400149
WNK1 kinase balances T cell adhesion versus migration in vivo.
PMID:27782176
Functional kinomics establishes a critical node of volume-sensitive cation-Cl(-) cotransporter regulation in the mammalian brain.
PMID:30280653
Blood-Brain Barrier: From Physiology to Disease and Back.
PMID:33597714
The structural basis of function and regulation of neuronal cotransporters NKCC1 and KCC2.
PMID:7629105
Primary structure, functional expression, and chromosomal localization of the bumetanide-sensitive Na-K-Cl cotransporter in human colon.
Reactome:R-HSA-426086
SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol
Reactome:R-HSA-426117
Cation-coupled Chloride cotransporters