Gene Ontology annotation through association of InterPro records with GO terms

Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

Annotation inferences using phylogenetic trees

Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara

Combined Automated Annotation using Multiple IEA Methods

CP110, a cell cycle-dependent CDK substrate, regulates centrosome duplication in human cells.

The Polo kinase Plk4 functions in centriole duplication.

CP110 cooperates with two calcium-binding proteins to regulate cytokinesis and genome stability.

Plk4-induced centriole biogenesis in human cells.

Cep97 and CP110 suppress a cilia assembly program.

CP110 suppresses primary cilia formation through its interaction with CEP290, a protein deficient in human ciliary disease.

Cep76, a centrosomal protein that specifically restrains centriole reduplication.

SCF(Cyclin F) controls centrosome homeostasis and mitotic fidelity through CP110 degradation.

Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.

Centriolar kinesin Kif24 interacts with CP110 to remodel microtubules and regulate ciliogenesis.

Neurl4, a novel daughter centriole protein, prevents formation of ectopic microtubule organizing centres.

Cyclin F-mediated degradation of ribonucleotide reductase M2 controls genome integrity and DNA repair.

miR-129-3p controls cilia assembly by regulating CP110 and actin dynamics.

USP33 regulates centrosome biogenesis via deubiquitination of the centriolar protein CP110.

The CP110-interacting proteins Talpid3 and Cep290 play overlapping and distinct roles in cilia assembly.

Human-chromatin-related protein interactions identify a demethylase complex required for chromosome segregation.

A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface.

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

M-Phase Phosphoprotein 9 regulates ciliogenesis by modulating CP110-CEP97 complex localization at the mother centriole.

Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.

Spatial centrosome proteome of human neural cells uncovers disease-relevant heterogeneity.

Centriolar cap proteins CP110 and CPAP control slow elongation of microtubule plus ends.

AJUBA facilitates AURKA autophosphorylation

AJUBA binds centrosome-associated AURKA

AURKA phosphorylates PLK1

BORA binds PLK1 and AURKA

Plk1-mediated phosphorylation of Nlp

Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome

Loss of C-Nap-1 from centrosomes

Dissociation of Phospho-Nlp from the centrosome

Recruitment of Plk1 to centrosomes

Association of NuMA with microtubules

Recruitment of CDK11p58 to the centrosomes

Translocation of NuMA to the centrosomes

C2CD3 binds the mother centriole

C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole

CP110 and CEP97 dissociate from the centriole

The distal appendage proteins recruit TTBK2

MARK4 binds ODF2 in the centriole

USP33 deubiquitinates CCP110,ARRB

TPX2 binds AURKA at centrosomes

TPX2 promotes AURKA autophosphorylation

The spinocerebellar ataxia-associated gene Tau tubulin kinase 2 controls the initiation of ciliogenesis.

Centrosomal protein CP110 controls maturation of the mother centriole during cilia biogenesis.

Deep research report (CCP110-deep-research-falcon.md)