GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000117
Electronic Gene Ontology annotations created by ARBA machine learning models
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
PMID:10357895
Notch-mediated segmentation and growth control of the Drosophila leg.
PMID:10357942
Composite signalling from Serrate and Delta establishes leg segments in Drosophila through Notch.
PMID:10504334
Ligand-receptor interactions and trans-endocytosis of Delta, Serrate and Notch: members of the Notch signalling pathway in Drosophila.
PMID:12445385
Notch signaling controls lineage specification during Drosophila larval hematopoiesis.
PMID:12569125
A Serrate-expressing signaling center controls Drosophila hematopoiesis.
PMID:12798300
Specification of cell fates within the salivary gland primordium.
PMID:12909620
Modulation of notch-ligand binding by protein O-fucosyltransferase 1 and fringe.
PMID:15760269
Two distinct E3 ubiquitin ligases have complementary functions in the regulation of delta and serrate signaling in Drosophila.
PMID:15829515
The ubiquitin ligase Drosophila Mind bomb promotes Notch signaling by regulating the localization and activity of Serrate and Delta.
PMID:16093323
The interplay between DSL proteins and ubiquitin ligases in Notch signaling.
PMID:16125166
Serrate-Notch signaling defines the scope of the initial denticle field by modulating EGFR activation.
PMID:1657403
Specific EGF repeats of Notch mediate interactions with Delta and Serrate: implications for Notch as a multifunctional receptor.
PMID:16643882
Notch pathway repression by vestigial is required to promote indirect flight muscle differentiation in Drosophila melanogaster.
PMID:17006545
Role of conserved intracellular motifs in Serrate signalling, cis-inhibition and endocytosis.
PMID:17070683
Stem cells signal to the niche through the Notch pathway in the Drosophila ovary.
PMID:17090721
Lobe and Serrate are required for cell survival during early eye development in Drosophila.
PMID:17923477
In vitro reconstitution of the modulation of Drosophila Notch-ligand binding by Fringe.
PMID:1840519
The Drosophila gene Serrate encodes an EGF-like transmembrane protein with a complex expression pattern in embryos and wing discs.
PMID:20176925
Notch ligand activity is modulated by glycosphingolipid membrane composition in Drosophila melanogaster.
PMID:20203305
Gene deletion screen for cardiomyopathy in adult Drosophila identifies a new notch ligand.
PMID:23152840
Sequential Notch signalling at the boundary of fringe expressing and non-expressing cells.
PMID:23970418
A Serrate-Notch-Canoe complex mediates essential interactions between glia and neuroepithelial cells during Drosophila optic lobe development.
PMID:24318532
An unexpected link between notch signaling and ROS in restricting the differentiation of hematopoietic progenitors in Drosophila.
PMID:28960177
Ubiquitylation-independent activation of Notch signalling by Delta.
PMID:35264151
Ubiquitylation is required for the incorporation of the Notch receptor into intraluminal vesicles to prevent prolonged and ligand-independent activation of the pathway.
PMID:8756291
The intracellular deletions of Delta and Serrate define dominant negative forms of the Drosophila Notch ligands.
PMID:9202123
Fringe modulates Notch-ligand interactions.
PMID:9310337
A dominant-negative form of Serrate acts as a general antagonist of Notch activation.
PMID:9553038
Delta and Serrate are redundant Notch ligands required for asymmetric cell divisions within the Drosophila sensory organ lineage.
Reactome:R-DME-2076706
Serrate binds Notch in cis
Reactome:R-DME-209226
DL/SER is ubiquitinated by E3 ubiquitination ligases (NEUR/MIB1)
file:DROME/Ser/Ser-deep-research-falcon.md
Ser deep research / notes (Ser-deep-research-falcon.md)