Manual transfer of annotations from one model organism to another based on sequence orthology
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Combined Automated Annotation using Multiple IEA Methods
RING finger protein AO7 supports NF-kappaB-mediated transcription by interacting with the transactivation domain of the p65 subunit.
EGF receptor-independent action of TGF-alpha protects Naked2 from AO7-mediated ubiquitylation and proteasomal degradation.
Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network.
A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome system.
Insights into Ubiquitination from the Unique Clamp-like Binding of the RING E3 AO7 to the E2 UbcH5B.
Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
Architecture of the human interactome defines protein communities and disease networks.
A reference map of the human binary protein interactome.
Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
An E3 ligase network engages GCN1 to promote the degradation of translation factors on stalled ribosomes.
Drug-induced eRF1 degradation promotes readthrough and reveals a new branch of ribosome quality control.
K6-linked ubiquitylation marks formaldehyde-induced RNA-protein crosslinks for resolution.
RNF14-dependent atypical ubiquitylation promotes translation-coupled resolution of RNA-protein crosslinks.
Multimodal cell maps as a foundation for structural and functional genomics.