GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000024
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000052
Gene Ontology annotation based on curation of immunofluorescence data
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
GO_REF:0000117
Electronic Gene Ontology annotations created by ARBA machine learning models
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
PMID:19250911
A role for NBR1 in autophagosomal degradation of ubiquitinated substrates.
PMID:19427866
Interactions with LC3 and polyubiquitin chains link nbr1 to autophagic protein turnover.
PMID:19822672
Spred2 interaction with the late endosomal protein NBR1 down-regulates fibroblast growth factor receptor signaling.
PMID:19946888
Defining the membrane proteome of NK cells.
PMID:20010802
Nix is a selective autophagy receptor for mitochondrial clearance.
PMID:20368287
Interactome mapping of the phosphatidylinositol 3-kinase-mammalian target of rapamycin pathway identifies deformed epidermal autoregulatory factor-1 as a new glycogen synthase kinase-3 interactor.
PMID:20417604
The selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein Alfy.
PMID:20562859
Network organization of the human autophagy system.
PMID:20808283
NBR1 is a new PB1 signalling adapter in Th2 differentiation and allergic airway inflammation in vivo.
PMID:21296869
Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy.
PMID:24692539
Solution structure of the ubiquitin-associated (UBA) domain of human autophagy receptor NBR1 and its interaction with ubiquitin and polyubiquitin.
PMID:25416956
A proteome-scale map of the human interactome network.
PMID:29568061
An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations.
PMID:30824926
Isoform-specific GSK3A activity is negatively correlated with human sperm motility.
PMID:33226137
Receptor-mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy.
PMID:33577621
The PB1 protein of influenza A virus inhibits the innate immune response by targeting MAVS for NBR1-mediated selective autophagic degradation.
PMID:33961781
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
PMID:34471133
Reconstitution defines the roles of p62, NBR1 and TAX1BP1 in ubiquitin condensate formation and autophagy initiation.
PMID:34524948
Global Proximity Interactome of the Human Macroautophagy Pathway.
PMID:24879152
Phosphorylation of NBR1 by GSK3 modulates protein aggregation.
PMID:35914352
NBR1 mediates autophagic degradation of IRF3 to negatively regulate type I interferon production.
PMID:38169523
Selective Autophagy Receptor NBR1 Retards Nucleus Pulposus Cell Senescence by Directing the Clearance of SRBD1.
Reactome:R-HSA-9664867
NBR1 binds MAP1LC3B
Reactome:R-HSA-9664880
MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1:NBR1
Reactome:R-HSA-9664881
NBR1 binds ATM:Ub-p-PEX5:SQSTM1