Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Gene Ontology annotation based on curation of immunofluorescence data

Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara

Combined Automated Annotation using Multiple IEA Methods

UniProtKB Q9H2F3 (3BHS7_HUMAN) - 3 beta-hydroxysteroid dehydrogenase type 7

The bile acid synthetic gene 3beta-hydroxy-Delta(5)-C(27)-steroid oxidoreductase is mutated in progressive intrahepatic cholestasis.

A proteome-scale map of the human interactome network.

A reference map of the human binary protein interactome.

7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one

Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol

Synthesis of bile acids and bile salts via 24-hydroxycholesterol

Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one

Synthesis of bile acids and bile salts via 27-hydroxycholesterol

Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one