Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Automatic Gene Ontology annotation based on Rhea mapping
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
Cell-autonomous regulation of cell and organ growth in Drosophila by Akt/PKB.
The conserved PI3'K/PTEN/Akt signaling pathway regulates both cell size and survival in Drosophila.
Regulation of Drosophila tracheal system development by protein kinase B.
dS6K-regulated cell growth is dPKB/dPI(3)K-independent, but requires dPDK1.
Akt regulates growth by directly phosphorylating Tsc2.
Control of cell number by Drosophila FOXO: downstream and feedback regulation of the insulin receptor pathway.
Coordinated functions of Akt/PKB and ETS1 in tubule formation.
Signaling from Akt to FRAP/TOR targets both 4E-BP and S6K in Drosophila melanogaster.
Drosophila PI3 kinase and Akt involved in insulin-stimulated proliferation and ERK pathway activation in Schneider cells.
dAkt kinase controls follicle cell size during Drosophila oogenesis.
PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth.
Requirement of Akt to mediate long-term synaptic depression in Drosophila.
Cytoplasmic activated protein kinase Akt regulates lipid-droplet accumulation in Drosophila nurse cells.
Insulin delays the progression of Drosophila cells through G2/M by activating the dTOR/dRaptor complex.
Re-evaluating AKT regulation: role of TOR complex 2 in tissue growth.
Discrete functions of rictor and raptor in cell growth regulation in Drosophila.
FOXO and insulin signaling regulate sensitivity of the circadian clock to oxidative stress.
Gliatrophic and gliatropic roles of PVF/PVR signaling during axon guidance.
The protein phosphatase PP2A-B' subunit Widerborst is a negative regulator of cytoplasmic activated Akt and lipid metabolism in Drosophila.
PDGF/VEGF signaling controls cell size in Drosophila.
The microRNA bantam functions in epithelial cells to regulate scaling growth of dendrite arbors in drosophila sensory neurons.
Dynamic switch of negative feedback regulation in Drosophila Akt-TOR signaling.
Genetic manipulation of AML1-ETO-induced expansion of hematopoietic precursors in a Drosophila model.
Drosophila insulin pathway mutants affect visual physiology and brain function besides growth, lipid, and carbohydrate metabolism.
A hormone-dependent module regulating energy balance.
MAPK/ERK signaling regulates insulin sensitivity to control glucose metabolism in Drosophila.
Regeneration of Drosophila sensory neuron axons and dendrites is regulated by the Akt pathway involving Pten and microRNA bantam.
Tuberous sclerosis complex regulates Drosophila neuromuscular junction growth via the TORC2/Akt pathway.
A Cullin1-based SCF E3 ubiquitin ligase targets the InR/PI3K/TOR pathway to regulate neuronal pruning.
The SCFSlimb E3 ligase complex regulates asymmetric division to inhibit neuroblast overgrowth.
The TORC1 inhibitors Nprl2 and Nprl3 mediate an adaptive response to amino-acid starvation in Drosophila.
Genetic dissection reveals that Akt is the critical kinase downstream of LRRK2 to phosphorylate and inhibit FOXO1, and promotes neuron survival.
A genetic strategy to measure circulating Drosophila insulin reveals genes regulating insulin production and secretion.
A systems-level interrogation identifies regulators of Drosophila blood cell number and survival.
A Drosophila Genome-Wide Screen Identifies Regulators of Steroid Hormone Production and Developmental Timing.
Spatial Activation of TORC1 Is Regulated by Hedgehog and E2F1 Signaling in the Drosophila Eye.
Intestinal Fork Head Regulates Nutrient Absorption and Promotes Longevity.
Innate Immune Signaling in Drosophila Blocks Insulin Signaling by Uncoupling PI(3,4,5)P(3) Production and Akt Activation.
Insulin signaling modulates border cell movement in Drosophila oogenesis.
The Hippo pathway integrates PI3K-Akt signals with mechanical and polarity cues to control tissue growth.
Meep, a Novel Regulator of Insulin Signaling, Supports Development and Insulin Sensitivity via Maintenance of Protein Homeostasis in Drosophila melanogaster.
Pvr and distinct downstream signaling factors are required for hemocyte spreading and epidermal wound closure at Drosophila larval wound sites.
A genetic strategy to measure insulin signaling regulation and physiology in Drosophila.
Developmental regulation of expression and activity of multiple forms of the Drosophila RAC protein kinase.
Genetic analysis of protein kinase B (AKT) in Drosophila.
Increased PIP3 levels recruit DAkt1 to the membrane
Activation of DAkt1 by DPDK1
DAkt1-mediated phosphorylation inactivates DFOXO
Activated DAkt1 phosphorylates TSC2 which inhibits the TSC1/2 complex