Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Gene Ontology annotation based on curation of immunofluorescence data
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Automatic Gene Ontology annotation based on Rhea mapping
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
Characterization of a new family of proteins that interact with the C-terminal region of the chromatin-remodeling factor CHD-3.
A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease.
A human protein-protein interaction network: a resource for annotating the proteome.
MBD2/NuRD and MBD3/NuRD, two distinct complexes with different biochemical and functional properties.
Chromatin remodeling proteins interact with pericentrin to regulate centrosome integrity.
Differential distribution of unmodified and phosphorylated histone deacetylase 2 in chromatin.
LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancer.
NuRD mediates activating and repressive functions of GATA-1 and FOG-1 during blood development.
Phosphorylated p68 RNA helicase activates Snail1 transcription by promoting HDAC1 dissociation from the Snail1 promoter.
KAP-1 phosphorylation regulates CHD3 nucleosome remodeling during the DNA double-strand break response.
A directed protein interaction network for investigating intracellular signal transduction.
NuRD suppresses pluripotency gene expression to promote transcriptional heterogeneity and lineage commitment.
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
PHF6 interacts with the nucleosome remodeling and deacetylation (NuRD) complex.
Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin.
Transcription Factor hDREF Is a Novel SUMO E3 Ligase of Mi2α.
CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.
CHD3 helicase domain mutations cause a neurodevelopmental syndrome with macrocephaly and impaired speech and language.
Cross-linking mass spectrometry reveals the structural topology of peripheral NuRD subunits relative to the core complex.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
Multimodal cell maps as a foundation for structural and functional genomics.
Molecular analysis of a major antigenic region of the 240-kD protein of Mi-2 autoantigen.
Characterization of the CHD family of proteins.
Identification of a human 17p-located cDNA encoding a protein of the Snf2-like helicase family.
The dermatomyositis-specific autoantigen Mi2 is a component of a complex containing histone deacetylase and nucleosome remodeling activities.
Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex.
HDAC1:2-containing complex deacetylate histones
MTA2-NuRD complex deacetylates TP53
SALL4 recruits NuRD to PTEN gene
ZBED1 (DREF) SUMOylates CHD3 with SUMO1
HDAC1:2-containing complex binds HDAC2 Inhibitors
CHD and CDK2AP subunits are recruited to NuRD
GATAD2A NuRD binds ZMYND8:ZNF532:ZNF592:ZNF687
ZNF827 and NR2C2,NR2F2 recruit NuRD to telomeric chromatin
NuRD deacetylates telomeric nucleosomes
NuRD hydrolyzes ATP to affect nucleosome organization
NuRD deacetylates nucleosomes
NuRD binds TCF19 at FBP1 gene
NuRD binds TCF19 at G6PC gene
NuRD binds TCF19 at PCK1 gene
NuRD binds Ikaros family member proteins
TRIM28 (KAP1) binds CHD3 (Mi-2alpha)
The NuRD component CHD3 promotes BMP signalling during cranial neural crest cell specification.
Covalent Modifications of Histone H3K9 Promote Binding of CHD3.
PHD domain-mediated E3 ligase activity directs intramolecular sumoylation of an adjacent bromodomain required for gene silencing.
CHD3 source-linked interaction, localization, ontology and assay evidence