Exact emitted record, retrieved 2026-09-10T14:34:41.431468+00:00.
Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC
UNC (CS 1). A selective 5hmC-reader function has not been demonstrated for DRS1. The frog Wdr76 donor text is itself an orthology inference. Moreover, sensitive Arabidopsis genomic-DNA assays found no appreciable 5hmC, limiting the proposed physiological reader context. These observations do not show that purified DRS1 cannot bind a synthetic 5hmC-containing DNA substrate, exclude trace oxidative products, or address RNA hydroxymethylcytosine. Thus the claim is not confidently scored as either correct or an absolute biochemical impossibility. PMID:25380728(https://pubmed.ncbi.nlm.nih.gov/25380728/); donor record.
The assessment concerns the selected accession Q9SAI7. Other emitted outputs and evidence context.