Gene Ontology annotation through association of InterPro records with GO terms

Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Gene Ontology annotation based on curation of immunofluorescence data

Gene Ontology annotation of human sequence-specific DNA binding transcription factors (DbTFs) based on the TFClass database

Electronic Gene Ontology annotations created by ARBA machine learning models

Combined Automated Annotation using Multiple IEA Methods

Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1.

Repression of the transcription factor Th-POK by Runx complexes in cytotoxic T cell development.

RUNX3 attenuates beta-catenin/T cell factors in intestinal tumorigenesis.

Brn3a regulates neuronal subtype specification in the trigeminal ganglion by promoting Runx expression during sensory differentiation.

Src kinase phosphorylates RUNX3 at tyrosine residues and localizes the protein in the cytoplasm.

The Runx transcriptional co-activator, CBFbeta, is essential for invasion of breast cancer cells.

Tumor suppressor, AT motif binding factor 1 (ATBF1), translocates to the nucleus with runt domain transcription factor 3 (RUNX3) in response to TGF-beta signal transduction.

Runx3 inactivation is a crucial early event in the development of lung adenocarcinoma.

Impact of cytosine methylation on DNA binding specificities of human transcription factors.

Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.

Ubiquitylation of RUNX3 by RNA-binding ubiquitin ligase MEX3C promotes tumorigenesis in lung adenocarcinoma.

Identification of a new murine runt domain-containing gene, Cbfa3, and localization of the human homolog, CBFA3, to chromosome 1p35-pter.

Cloning, mapping and expression of PEBP2 alpha C, a third gene encoding the mammalian Runt domain.

AML1, AML2, and AML3, the human members of the runt domain gene-family: cDNA structure, expression, and chromosomal localization.

Transcriptional repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors.

CBFB binds RUNX3

RUNX3 binds ZFHX3

RUNX3 binds SMAD3 and SMAD4

The complex of RUNX3, SMAD3 and SMAD4 binds the CDKN1A gene promoter

RUNX3 binds the JAG1 gene promoter

RUNX3 binds the NOTCH1 coactivator complex

RUNX3:NOTCH1 coactivator complex binds the HES1 gene promoter

RUNX3 binds SRC

SRC phosphorylates RUNX3

RUNX3 translocates to the nucleus

RUNX3:CBFB binds the ITGAL gene,(ITGA4 gene) promoter

RUNX3 binds CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7)

RUNX3 binds TEADs and YAP1

RUNX3 binds the RUNX1 promoter

RUNX3 binds EP300

EP300 acetylates RUNX3

Acetylated RUNX3 binds to BRD2

CCND1 binds RUNX3 and displaces EP300

CCND1 recruits HDAC4 to RUNX3

HDAC4 deacetylates RUNX3

RUNX3 binds TP53

RUNX3 binds the BCL2L11 (BIM) gene

MDM2 binds RUNX3

MDM2 polyubiquitinates RUNX3

Polyubiquitinated RUNX3 translocates to the cytosol

Polyubiquitinated RUNX3 is degraded by the proteasome

SMURFs ubiquitinate RUNX3

Falcon deep research synthesis for RUNX3