Complete sequencing and characterization of 21,243 full-length human cDNAs.
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Two isoforms of GABA(A) receptor beta2 subunit with different electrophysiological properties: Differential expression and genotypical correlations in schizophrenia.
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The authentic abstract reports faster rundown during repeated GABA stimulation for recombinant receptors containing the long beta2 form than for receptors containing the short form in HEK293 cells. The assay supports splice-dependent receptor behavior; cohort associations do not establish an additional disease process.
"a steeper current rundown upon repetitive GABA activation"
A new naturally occurring GABA(A) receptor subunit partnership with high sensitivity to ethanol.
alpha1beta2delta, a silent GABAA receptor: recruitment by tracazolate and neurosteroids.
Large-scale proteomics and phosphoproteomics of urinary exosomes.
Alternative-splicing in the exon-10 region of GABA(A) receptor beta(2) subunit gene: relationships between novel isoforms and psychotic disorders.
GABA(A) receptors can initiate the formation of functional inhibitory GABAergic synapses.
Palmitoylation of gephyrin controls receptor clustering and plasticity of GABAergic synapses.
A novel variant in GABRB2 associated with intellectual disability and epilepsy.
Inhibitory synapse formation in a co-culture model incorporating GABAergic medium spiny neurons and HEK293 cells stably expressing GABAA receptors.
A de novo missense mutation of GABRB2 causes early myoclonic encephalopathy.
GABA(A) Receptors and the Diversity in their Structure and Pharmacology.
High Rate of Recurrent De Novo Mutations in Developmental and Epileptic Encephalopathies.
Structure of a human synaptic GABA(A) receptor.
Regulation of GABA(A)Rs by Transmembrane Accessory Proteins.
Differential assembly diversifies GABA(A) receptor structures and signalling.
Extra-Synaptic GABA(A) Receptor Potentiation and Neurosteroid-Induced Learning Deficits Are Inhibited by GR3027, a GABA(A) Modulating Steroid Antagonist.
Resolving native GABA(A) receptor structures from the human brain.
Cloning, sequence analysis and expression of two forms of mRNA coding for the human beta 2 subunit of the GABAA receptor.
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The authentic abstract reports human beta2 cDNAs differing by a 114-base-pair insertion and expression of the longer transcript in the sampled brain regions. Exact modern splice identities are supplied by the independently verified UniProt sequences, not inferred from historical names.
"The two sequences differ by a 114 base pair insertion."
Role of the beta subunit in determining the pharmacology of human gamma-aminobutyric acid type A receptors.
Segregation of different GABAA receptors to synaptic and extrasynaptic membranes of cerebellar granule cells.
Functional role of GABAergic innervation of the cochlea: phenotypic analysis of mice lacking GABA(A) receptor subunits alpha 1, alpha 2, alpha 5, alpha 6, beta 2, beta 3, or delta.
Interneuron- and GABA(A) receptor-specific inhibitory synaptic plasticity in cerebellar Purkinje cells.
γ-Aminobutyric Acid Type A (GABAA) Receptor Subunits Play a Direct Structural Role in Synaptic Contact Formation via Their N-terminal Extracellular Domains.
Histamine action on vertebrate GABAA receptors: direct channel gating and potentiation of GABA responses.
The kinesin KIF21B participates in the cell surface delivery of γ2 subunit-containing GABAA receptors.
Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
GABR heteropentamers:GABA transport Cl- from extracellular region to cytosol
Gamma-aminobutyric acid receptor subunit beta-2