Annotation inferences using phylogenetic trees
Gene Ontology annotation based on curation of immunofluorescence data
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
Mammalian suppressor-of-fused modulates nuclear-cytoplasmic shuttling of Gli-1.
Characterization of the human suppressor of fused, a negative regulator of the zinc-finger transcription factor Gli.
Gli regulation by the opposing activities of fused and suppressor of fused.
The sonic hedgehog-patched-gli pathway in human development and disease.
Towards a proteome-scale map of the human protein-protein interaction network.
An atlas of combinatorial transcriptional regulation in mouse and man.
Dual function of UNC-51-like kinase 3 (Ulk3) in the Sonic hedgehog signaling pathway.
The crosstalk of mTOR/S6K1 and Hedgehog pathways.
Parallel SCF adaptor capture proteomics reveals a role for SCFFBXL17 in NRF2 activation via BACH1 repressor turnover.
Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci.
Structural basis of SUFU-GLI interaction in human Hedgehog signalling regulation.
Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network.
A proteome-scale map of the human interactome network.
Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.
SCF (Fbxl17) ubiquitylation of Sufu regulates Hedgehog signaling and medulloblastoma development.
Architecture of the human interactome defines protein communities and disease networks.
Hypomorphic Recessive Variants in SUFU Impair the Sonic Hedgehog Pathway and Cause Joubert Syndrome with Cranio-facial and Skeletal Defects.
The interactome of KRAB zinc finger proteins reveals the evolutionary history of their functional diversification.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.
A reference map of the human binary protein interactome.
Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
Human transcription factor protein interaction networks.
Systematic discovery of mutation-directed neo-protein-protein interactions in cancer.
ERK2 MAP kinase regulates SUFU binding by multisite phosphorylation of GLI1.
Positive regulation of Hedgehog signaling via phosphorylation of GLI2/GLI3 by DYRK2 kinase.
Multimodal cell maps as a foundation for structural and functional genomics.
CK1 phosphorylates p-GLI3
GSK3 phosphorylates p-GLI3
NUMB:ITCH bind and ubiquitnate GLI1
SCF(beta-TrCP) ubiquitinates p-GLI1
SCF(beta-TrCP) ubiquitinates p-GLI3
GLI3 is partially degraded by the proteasome to yield the GLI3 repressor
GLI1 is degraded by the proteasome after ubiquitination by beta-TrCP
GLI1 is degraded by the proteasome after ubiquitination by ITCH
The intraflagellar transport A (IFT-A) complex is required for the transit of GLI:SUFU complexes to the ciliary base
The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip
GLI:SUFU translocates to the ciliary tip in response to Hh signaling
Gli2is degraded by the proteasome