BAM1 (BARELY ANY MERISTEM 1, At5g65700; UniProt O49545) curation notes

Identity

The BAM1 symbol also matches beta-amylase 1 (Q9LIR6, At3g23920), so the gene was fetched by accession O49545 and the AGI locus At5g65700 was verified.

BAM1 is a CLV1-clade LRR-RK. bam1 bam2 bam3 mutants lose stem cells, and BAM genes also act in leaf vasculature, male gametophyte and ovule development PMID:16367950.
BAM1/BAM2 act as receptors in parallel with CLV1. clv1 nulls are weak because of BAM activity, and bam mutants suppress clv3, possibly by sequestering ligand in the meristem flanks PMID:18780746.
BAM1 binds CLV3 directly (radioligand Kd 26 nM PMID:20626648; photoaffinity labelling PMID:25754504). clv1 bam1 has an enlarged SAM with expanded WUS PMID:25754504.
BAM ligand specificity is broader than that of CLV1/CLV2 PMID:20626648.
In clv1 mutants, BAM genes are expressed ectopically and buffer the meristem PMID:28355208.
BAM1 phosphorylates PBL34/35/36, and CLV3-induced MPK3/6 phosphorylation depends on CLV1/BAM1 PMID:34935965.
CLE25/26/45-BAM1/3-CIK controls protophloem differentiation PMID:34651321.
BAM1/BAM2 are needed for early anther cell layers PMID:16751349.

Core MF is GO:0004675 transmembrane receptor protein serine/threonine kinase activity, reached by MODIFYing the GOA IDA GO:0004674 row (PMID:34651321) to it, with support from PMID:25754504 and PMID:20626648 (direct CLV3 binding). The process GO:0007178 is also proposed as NEW.
The CLE peptide IPI rows are MODIFIED to peptide hormone binding (GO:0017046, as in the CLV1 review). The RLCK IPI rows are MODIFIED to protein kinase binding.
The CSI-LRR high-throughput ectodomain protein binding rows are REMOVED (bare protein binding, no functional information).
The IBA hormone-mediated signaling row (a node seeded by BRI1/BRL) is kept as non-core.
Deep research (falcon) attempted 2026-10-05 and failed with HTTP 402 Payment Required. No deep-research file exists for BAM1.

Dropped the NEW GO:0004675 row (redundant with its direct parent GO:0004674); instead the GO:0004674 IDA row is MODIFIED to GO:0004675. The IEA GO:0004674 (EC mapping) row and the InterPro IEA GO:0004672 row are also MODIFIED to GO:0004675 so that all kinase rows are consistent. The NEW GO:0007178 row is unchanged.