Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Gene Ontology annotation based on curation of immunofluorescence data
Combined Automated Annotation using Multiple IEA Methods
Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits.
The human SWI-SNF complex protein p270 is an ARID family member with non-sequence-specific DNA binding activity.
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Human p270 binds DNA without sequence preference.
"In contrast, p270 shows no sequence preference
in its DNA binding activity"
Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF.
The human SWI/SNF-B chromatin-remodeling complex is related to yeast rsc and localizes at kinetochores of mitotic chromosomes.
Mammalian SWI/SNF complexes promote MyoD-mediated muscle differentiation.
The murine SNF5/INI1 chromatin remodeling factor is essential for embryonic development and tumor suppression.
Fanconi anemia protein, FANCA, associates with BRG1, a component of the human SWI/SNF complex.
Selectivity of chromatin-remodelling cofactors for ligand-activated transcription.
SWI/SNF chromatin remodeling and cancer.
Cloning and characterization of hELD/OSA1, a novel BRG1 interacting protein.
Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes.
REST repression of neuronal genes requires components of the hSWI.SNF complex.
Largest subunits of the human SWI/SNF chromatin-remodeling complex promote transcriptional activation by steroid hormone receptors.
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Human hOsa1 associates with SWI/SNF-A and promotes steroid-receptor transcription.
"In cultured mammalian
cells, hOsa1 and hOsa2 stimulate transcription by the glucocorticoid, estrogen,
and androgen receptors."
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Human hOsa proteins associate with BRG1 and hBRM through their C-terminal region.
"Co-precipitation studies indicate that hOsa1 and hOsa2 associate with BRG1 and
hBRM through the C-terminal domain of hOsa."
The SWI/SNF chromatin-remodeling factor stimulates repair by human excision nuclease in the mononucleosome core particle.
Identification of a polymorphic, neuron-specific chromatin remodeling complex.
DNA-binding properties of ARID family proteins.
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Human p270 ARID binds DNA without sequence specificity in the reported assays.
"In contrast to Dri, p270 (ARID1A) binds in a non-specific manner, binding to all fragments offered to it, showing selectivity only for longer fragments (>200 bp) at higher salt concentrations, presumably because longer fragments offer multiple binding sites."
PBAF chromatin-remodeling complex requires a novel specificity subunit, BAF200, to regulate expression of selective interferon-responsive genes.
Mammalian SWI/SNF complexes facilitate DNA double-strand break repair by promoting gamma-H2AX induction.
Separation and Quantification of Some Alkaloids from Fumaria parviflora by Capillary Isotachophoresis1.
The core component of the mammalian SWI/SNF complex SMARCD3/BAF60c is a coactivator for the nuclear retinoic acid receptor.
Regulation of dendritic development by neuron-specific chromatin remodeling complexes.
BRD7, a novel PBAF-specific SWI/SNF subunit, is required for target gene activation and repression in embryonic stem cells.
An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency.
HIC1 interacts with a specific subunit of SWI/SNF complexes, ARID1A/BAF250A.
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HIC1 recruits ARID1A-containing SWI/SNF complexes in transcriptional repression.
"sequential chromatin immunoprecipitation
(ChIP-reChIP) experiments demonstrated that HIC1 represses E2F1 through the
recruitment of anti-proliferative SWI/SNF complexes containing ARID1A."
ARID1a-DNA interactions are required for promoter occupancy by SWI/SNF.
Reversible disruption of mSWI/SNF (BAF) complexes by the SS18-SSX oncogenic fusion in synovial sarcoma.
BAF complexes facilitate decatenation of DNA by topoisomerase IIα.
Requirement for PBAF in transcriptional repression and repair at DNA breaks in actively transcribed regions of chromatin.
Identification and functional characterization of a novel bipartite nuclear localization sequence in ARID1A.
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei.
Recurrent SMARCB1 Mutations Reveal a Nucleosome Acidic Patch Interaction Site That Potentiates mSWI/SNF Complex Chromatin Remodeling.
A protein interaction landscape of breast cancer.
OpenCell: Endogenous tagging for the cartography of human cellular organization.
Pioneer factor ASCL1 cooperates with the mSWI/SNF complex at distal regulatory elements to regulate human neural differentiation.
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ASCL1 and ARID1A coassociate in DIV24 human neural cultures.
"Immunoprecipitation followed by Western blot analysis in DIV24 neural cultures showing reciprocal coimmunoprecipitation of ASCL1 and SMARCC1 or ARID1A."
Diversity and specialization of mammalian SWI/SNF complexes.
Purification and biochemical heterogeneity of the mammalian SWI-SNF complex.
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Purified BRG1-containing complexes disrupt nucleosomes and facilitate activator access.
"Complexes containing BRG1 can disrupt nucleosomes and
facilitate the binding of GAL4-VP16 to a nucleosomal template similar to the
yeast SWI-SNF complex."
p300/CREB binding protein-related protein p270 is a component of mammalian SWI/SNF complexes.
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Human p270 is an integral SWI/SNF subunit.
"Purification and
analysis of various proteins in this group reveals that they are components of
the human SWI/SNF complex and that p270 is an integral member of this complex."
ARID1A binds CDH1 gene promoter
MITF-M dimer and the SWI/SNF complex bind the TYRP1 promoter
ARID1 binds SMARCC1 dimer:SMARCD1:SMARCE1:SMARCB1
DPF1,2,3 binds SMARCC1 dimer:SMARCD1:SMARCE1:SMARCB1:ARID1
SS18-containing ATPase complex binds SMARCC1 dimer:SMARCD1:SMARCE1:SMARCB1:ARID1:DPF1,2,3
Formation of neuronal progenitor BAF (npBAF)
DPF2, PHF10 bind SMARCC1:SMARCC2 dimer:SMARD1:ARID1A
SMARCA4, BCL11A,B-containing ATPase module binds SMARCC1:SMACC2 dimer:SMARCD1:SMARCE1:SMARCB1:ARID1A:DPF2, PHF10
ARID1A binds SMARCC1:SMARCC2 dimer:SMARCD1:SMARCE1:SMARCB1
Manual ARID1A source reading and annotation scope