GO_REF:0000002

Gene Ontology annotation through association of InterPro records with GO terms

InterPro supplies the broad transaminase term from IPR004637 (Dat) and the PLP-binding term from IPR005814 (Aminotrans_3).

GO_REF:0000033

Annotation inferences using phylogenetic trees

PAINT node PTN002461253 of PTHR43552, seeded by Q9I168 itself, propagates transaminase activity across the diaminobutyrate aminotransferase clade.

PMID:12686626

Identification and characterization of novel pyoverdine synthesis genes in Pseudomonas aeruginosa.

"The candidate genes were mutated and the effects of the mutations on pyoverdine production were determined. Eight new pvd genes were identified."

PMID:15317763

Functional characterization of an aminotransferase required for pyoverdine siderophore biosynthesis in Pseudomonas aeruginosa PAO1.

"PvdH was found to catalyze an aminotransferase reaction, interconverting aspartate beta-semialdehyde and l-2,4-diaminobutyrate."
"Both pvdH and asd (encoding aspartate beta-semialdehyde dehydrogenase) knockout mutants of Pseudomonas aeruginosa PAO1 were unable to synthesize pyoverdine under iron-limiting conditions in the absence of l-2,4-diaminobutyrate in the culture media."
"Steady-state kinetic analysis with a novel coupled assay established that the enzyme adopts a ping-pong kinetic mechanism and has the highest specificity for alpha-ketoglutarate."
"These homologues were found in the DNA loci of the corresponding genomes that contain other pyoverdine synthesis genes."

file:PSEAE/pvdH/pvdH-uniprot.txt

UniProtKB entry Q9I168 (PvdH, PA2413)

"DR NCBIfam; TIGR00709; dat; 1."
"DR InterPro; IPR004637; Dat."
"DR PROSITE; PS00600; AA_TRANSFER_CLASS_3; 1."
"SIMILARITY: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family."

file:interpro/panther/PTHR43552/PTHR43552-paint.tsv

PAINT IBD nodes for PTHR43552