Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB Subcellular Location vocabulary mapping
Combined Automated Annotation using Multiple IEA Methods
Towards a proteome-scale map of the human protein-protein interaction network.
hnulp1, a basic helix-loop-helix protein with a novel transcriptional repressive domain, inhibits transcriptional activity of serum response factor.
Nuclear localized protein-1 (Nulp1) increases cell death of human osteosarcoma cells and binds the X-linked inhibitor of apoptosis protein.
-
Reports TCF25/Nulp1 nuclear localization, a pro-cell-death effect, and XIAP binding (legacy, pre-RQC function).
An empirical framework for binary interactome mapping.
Next-generation sequencing to generate interactome datasets.
Differential protein-protein interactions of LRRK1 and LRRK2 indicate roles in distinct cellular signaling pathways.
A proteome-scale map of the human interactome network.
Architecture of the human interactome defines protein communities and disease networks.
Release of Ubiquitinated and Non-ubiquitinated Nascent Chains from Stalled Mammalian Ribosomal Complexes by ANKZF1 and Ptrh1.
-
TCF25 ensures preferential formation of the K48-ubiquitin linkage during RQC ubiquitination of stalled nascent chains by LTN1.
-
Defines the mammalian RQC pathway in which 60S RNCs associate with NEMF, which recruits Listerin to ubiquitinate nascent chains.
Parkinson's disease-associated LRRK2-G2019S mutant acts through regulation of SERCA activity to control ER stress in astrocytes.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.
A reference map of the human binary protein interactome.
Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
OpenCell: Endogenous tagging for the cartography of human cellular organization.
Ribosome-associated quality-control mechanisms from bacteria to humans.
Reactome: TCF25 cytosol localization
Reactome: TCF25 cytosol localization
Reactome: TCF25 cytosol localization
UniProt entry Q9BQ70 (TCF25_HUMAN), Ribosome quality control complex subunit TCF25