GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000024
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000052
Gene Ontology annotation based on curation of immunofluorescence data
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
GO_REF:0000117
Electronic Gene Ontology annotations created by ARBA machine learning models
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
PMID:16186108
Tyrosine 740 phosphorylation of discoidin domain receptor 2 by Src stimulates intramolecular autophosphorylation and Shc signaling complex formation.
PMID:16626936
Sensing extracellular matrix: an update on discoidin domain receptor function.
PMID:17703188
Structural basis of the collagen-binding mode of discoidin domain receptor 2.
PMID:20004161
Crystallographic insight into collagen recognition by discoidin domain receptor 2.
PMID:20564243
Transcriptional upregulation of DDR2 by ATF4 facilitates osteoblastic differentiation through p38 MAPK-mediated Runx2 activation.
PMID:21423176
Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation.
PMID:22939624
Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.
PMID:25036637
A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways.
PMID:30449416
Recurrent, Activating Variants in the Receptor Tyrosine Kinase DDR2 Cause Warburg-Cinotti Syndrome.
PMID:33961781
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
PMID:35384245
Physical and functional interactome atlas of human receptor tyrosine kinases.
PMID:9659899
The discoidin domain receptor tyrosine kinases are activated by collagen.
Reactome:R-HSA-2465890
DDR2 binds collagen type I, II, III, V, X fibrils
PMID:11375938
The collagen receptor DDR2 regulates proliferation and its elimination leads to dwarfism.
PMID:11723120
Discoidin domain receptor 2 regulates fibroblast proliferation and migration through the extracellular matrix in association with transcriptional activation of matrix metalloproteinase-2.
PMID:15218324
Localization of discoidin domain receptors in rat kidney.
PMID:16087782
Regulation of discoidin domain receptor 2 by cyclic mechanical stretch in cultured rat vascular smooth muscle cells.
PMID:18664364
Hypoxia induces discoidin domain receptor-2 expression via the p38 pathway in vascular smooth muscle cells to increase their migration.
PMID:19900459
Inhibition of collagen fibrillogenesis by cells expressing soluble extracellular domains of DDR1 and DDR2.
PMID:23409069
RNA interference against discoidin domain receptor 2 ameliorates alcoholic liver disease in rats.
PMID:24938620
Experimental chondrocyte hypertrophy is promoted by the activation of discoidin domain receptor 2.
PMID:26674152
Molecular basis and functional significance of Angiotensin II-induced increase in Discoidin Domain Receptor 2 gene expression in cardiac fibroblasts.
PMID:32412792
Coordinated regulation of cell survival and cell cycle pathways by DDR2-dependent SRF transcription factor in cardiac fibroblasts.