Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Combined Automated Annotation using Multiple IEA Methods
Differential regulation of p53 and p21 by MKRN1 E3 ligase controls cell cycle arrest and apoptosis.
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
The RNA-binding ubiquitin ligase MKRN1 functions in ribosome-associated quality control of poly(A) translation.
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MKRN1 binds PABPC1 and polysomes upstream of poly(A) tails, promotes ribosome stalling at A-rich sequences, and ubiquitinates RPS10 and PABPC1, acting in ribosome-associated quality control of poly(A) translation.
A reference map of the human binary protein interactome.
Reactome pathway annotation (cytosol localization)
Reactome pathway annotation (MKRN1 ubiquitin ligase activity)
UniProt entry Q9UHC7 (MKRN1_HUMAN)
GOA annotations for MKRN1