MFN2 notes
Deep research: not run (falcon times out in this environment; perplexity-lite unavailable). Review based on cached publications and UniProt.
- Fusion GTPase: PMID:11181170; catalytic mutants inactive PMID:28114303.
- ER-mitochondria tethering proposal PMID:19052620; contested in later literature, so used only as a MODIFY target (GO:0140474) on that paper's row, not as a core function.
- Parkin receptor PMID:23620051.
- HSG anti-proliferative role is fusion-independent PMID:15322553; PASMC miR-17 study gives opposite sign (positive regulation of proliferation) - kept non-core.
- GO:0160204 (mitochondrion-mitochondrion outer membrane tether activity) would describe trans-tethering, but no MFN2-specific direct tethering assay is in the cached set; not asserted.