The spinocerebellar ataxia-associated gene Tau tubulin kinase 2 controls the initiation of ciliogenesis.

TTBK2 kinase substrate specificity and the impact of spinocerebellar-ataxia-causing mutations on expression, activity, localization and development.

M-Phase Phosphoprotein 9 regulates ciliogenesis by modulating CP110-CEP97 complex localization at the mother centriole.

Phosphorylation of CEP83 by TTBK2 is necessary for cilia initiation.

Cep164 triggers ciliogenesis by recruiting Tau tubulin kinase 2 to the mother centriole.

Binding to Cep164, but not EB1, is essential for centriolar localization of TTBK2 and its function in ciliogenesis.

TTBK2 with EB1/3 regulates microtubule dynamics in migrating cells through KIF2A phosphorylation.

Spinocerebellar ataxia type 11-associated alleles of Ttbk2 dominantly interfere with ciliogenesis and cilium stability.

MCRS1 associates with cytoplasmic dynein and mediates pericentrosomal material recruitment.

Roles of tau protein in health and disease.

Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach.

Deep research report on TTBK2 (falcon)

Intrinsic heterogeneity of primary cilia revealed through spatial proteomics.

Gene Ontology annotation through association of InterPro records with GO terms

Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Gene Ontology annotation based on curation of immunofluorescence data

Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara

Automatic Gene Ontology annotation based on Rhea mapping

Electronic Gene Ontology annotations created by ARBA machine learning models

Combined Automated Annotation using Multiple IEA Methods

Exome capture reveals ZNF423 and CEP164 mutations, linking renal ciliopathies to DNA damage response signaling.

A proteome-scale map of the human interactome network.

A reference map of the human binary protein interactome.

Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.

RAB3IP stimulates nucleotide exchange on RAB8A

CP110 and CEP97 dissociate from the centriole

The distal appendage proteins recruit TTBK2

Recruitment of transition zone proteins

MARK4 binds ODF2 in the centriole

CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body