Gene Ontology annotation through association of InterPro records with GO terms

Annotation inferences using phylogenetic trees

Combined Automated Annotation using Multiple IEA Methods

Falcon deep research report for human CCL4

Extracellular cysteines of CCR5 are required for chemokine binding, but dispensable for HIV-1 coreceptor activity.

Lipopolysaccharide inhibits HIV-1 infection of monocyte- derived macrophages through direct and sustained down-regulation of CC chemokine receptor 5.

In vitro correlates of HIV-2-mediated HIV-1 protection.

Induction of interactions between CD44 and hyaluronic acid by a short exposure of human T cells to diverse pro-inflammatory mediators.

Natural truncation of the chemokine MIP-1 beta /CCL4 affects receptor specificity but not anti-HIV-1 activity.

Polymerization of MIP-1 chemokine (CCL3 and CCL4) and clearance of MIP-1 by insulin-degrading enzyme.

Identification, cloning, and characterization of an immune activation gene.

Mitogenic activation of human T cells induces two closely related genes which share structural similarities with a new family of secreted factors.

A proteome-scale map of the human interactome network.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.

A reference map of the human binary protein interactome.

Monocyte chemotactic protein-3 (MCP3) interacts with multiple leukocyte receptors. C-C CKR1, a receptor for macrophage inflammatory protein-1 alpha/Rantes, is also a functional receptor for MCP3.

Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8+ T cells.

Cloning and functional expression of CC CKR5, a human monocyte CC chemokine receptor selective for MIP-1(alpha), MIP-1(beta), and RANTES.

Dendritic cells express multiple chemokine receptors used as coreceptors for HIV entry.

CXCR4 and CCR5 on human thymocytes: biological function and role in HIV-1 infection.

Roles of chemokines and receptor polarization in NK-target cell interactions.

Liganded Gi-activating GPCR acts as a GEF for Gi

Receptor ACKR2 binds most inflammatory CC chemokines

IL10 negatively regulates extracellular inflammatory mediators

The Ligand:GPCR:Gi complex dissociates

Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi