Gene Ontology annotation through association of InterPro records with GO terms
Gene Ontology annotation based on UniPathway vocabulary mapping
Combined Automated Annotation using Multiple IEA Methods
Complete genome sequence and comparative analysis of the metabolically versatile Pseudomonas putida KT2440
A second chromosomal copy of the catA gene endows Pseudomonas putida mt-2 with an enzymatic safety valve for excess of catechol
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CatA2 relieves catechol surplus when benzoate induces the ortho pathway in KT2440.
"The data consistently indicated that induction of the ortho pathway by benzoate plasmid-less strain P. putida KT2440 led to catechol surplus, the toxicity of which at high concentrations being counteracted by CatA2."
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P. putida mt-2 has a second chromosomal copy of the catA gene (catA2) located downstream of the ben operon encoding an additional catechol 1,2-dioxygenase.
"P. putida mt-2 has a second chromosomal copy of the catA gene (named catA2) located downstream of the ben operon that encodes an additional catechol-1,2-dioxygenase."
Genomic analysis of the aromatic catabolic pathways from Pseudomonas putida KT2440
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KT2440 has catechol (cat genes) and protocatechuate (pca genes) branches of the beta-ketoadipate pathway.
"the protocatechuate (pca genes) and catechol (cat genes) branches of the beta-ketoadipate pathway"
Generation of a catR deficient mutant of P. putida KT2440 that produces cis, cis-muconate from benzoate at high rate and yield
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Loss of cat operon induction in a KT2440 catR mutant blocks growth on benzoate and causes cis,cis-muconate accumulation.
"The mutant was no longer able to grow using benzoate as a sole carbon source, but co-metabolized benzoate to cis, cis-muconate during growth on glucose, which accumulated in the growth medium."
The 1.8 A crystal structure of catechol 1,2-dioxygenase reveals a novel hydrophobic helical zipper as a subunit linker.
DNA sequence of the Acinetobacter calcoaceticus catechol 1,2-dioxygenase I structural gene catA: evidence for evolutionary divergence of intradiol dioxygenases by acquisition of DNA sequence repetitions.
Falcon deep research report for catA-I (PP_3713)