Manual transfer of experimentally-verified manual GO annotation data to orthologs using sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB Subcellular Location vocabulary mapping
Combined Automated Annotation using Multiple IEA Methods
Molecular cloning and expression of a transformation-sensitive human protein containing the TPR motif and sharing identity to the stress-inducible yeast protein STI1.
Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis.
Regulation of epidermal growth factor receptor trafficking by lysine deacetylase HDAC6.
Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells.
Mixed Hsp90-cochaperone complexes are important for the progression of the reaction cycle.
Label-free quantitative proteomics and SAINT analysis enable interactome mapping for the human Ser/Thr protein phosphatase 5.
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity.
Distinct roles of molecular chaperones HSP90α and HSP90β in the biogenesis of KCNQ4 channels.
SMYD2-dependent HSP90 methylation promotes cancer cell proliferation by regulating the chaperone complex formation.
A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways.
The FNIP co-chaperones decelerate the Hsp90 chaperone cycle and enhance drug binding.
Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.
Architecture of the human interactome defines protein communities and disease networks.
Tumor suppressor Tsc1 is a new Hsp90 co-chaperone that facilitates folding of kinase and non-kinase clients.
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HOP/STIP1 is a component of the HSP70-HSP90 multichaperone complex (with CDC37, PPP5C, p23, TSC1) that matures kinase and non-kinase clients.
Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRAS(G13D).
Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
Human transcription factor protein interaction networks.
OpenCell: Endogenous tagging for the cartography of human cellular organization.
Multimodal cell maps as a foundation for structural and functional genomics.
HSF1 activation / cytosolic chaperone pathway
Cytosolic chaperone (HSP90) pathway
Cytosolic chaperone (HSP90) pathway
Cytosolic chaperone (HSP90) pathway
Cytosolic chaperone (HSP90) pathway
Cytosolic chaperone (HSP90) pathway
Cytosolic chaperone (HSP90) pathway
UniProt entry P31948 (STIP1_HUMAN), stress-induced phosphoprotein 1 / HOP