Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Gene Ontology annotation based on curation of immunofluorescence data

Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara

Fam198a, a member of secreted kinase, secrets through caveolae biogenesis pathway.

Combined Automated Annotation using Multiple IEA Methods

Vectorial proteomics reveal targeting, phosphorylation and specific fragmentation of polymerase I and transcript release factor (PTRF) at the surface of caveolae in human adipocytes.

Association and insulin regulated translocation of hormone-sensitive lipase with PTRF.

A critical role of cavin (polymerase I and transcript release factor) in caveolae formation and organization.

SDPR induces membrane curvature and functions in the formation of caveolae.

Human PTRF mutations cause secondary deficiency of caveolins resulting in muscular dystrophy with generalized lipodystrophy.

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.

Molecular composition and ultrastructure of the caveolar coat complex.

MURC/Cavin-4 facilitates recruitment of ERK to caveolae and concentric cardiac hypertrophy induced by α1-adrenergic receptors.

Flotillin-1 facilitates toll-like receptor 3 signaling in human endothelial cells.

Architecture of the human interactome defines protein communities and disease networks.

A reference map of the human binary protein interactome.

Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.

Multimodal cell maps as a foundation for structural and functional genomics.

Cloning and functional characterization of PTRF, a novel protein which induces dissociation of paused ternary transcription complexes.

Dissociation of PTRF:Polymerase I/Nascent Pre rRNA Complex:TTF-I:Sal Box

PTRF Binds the Polymerase I Transcription Complex/Nascent Pre rRNA Complex paused at the TTF-I:Sal Box

UniProtKB Q6NZI2 (CAVN1_HUMAN): reviewed CAVIN1 record

The transcript release factor PTRF augments ribosomal gene transcription by facilitating reinitiation of RNA polymerase I.

PTRF/Cavin-1 promotes efficient ribosomal RNA transcription in response to metabolic challenges.