Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Gene Ontology annotation based on curation of immunofluorescence data
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Combined Automated Annotation using Multiple IEA Methods
Fumarase: a mitochondrial metabolic enzyme and a cytosolic/nuclear component of the DNA damage response.
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
Phosphoproteome analysis of functional mitochondria isolated from resting human muscle reveals extensive phosphorylation of inner membrane protein complexes and enzymes.
A proteome-scale map of the human interactome network.
Local generation of fumarate promotes DNA repair through inhibition of histone H3 demethylation.
Human Fumarate Hydratase Is Dual Localized by an Alternative Transcription Initiation Mechanism.
Adipose-Specific Deficiency of Fumarate Hydratase in Mice Protects Against Obesity, Hepatic Steatosis, and Insulin Resistance.
Biochemical Characterization of Two Clinically-Relevant Human Fumarase Variants Defective for Oligomerization.
Structural, biochemical and biophysical characterization of recombinant human fumarate hydratase.
A reference map of the human binary protein interactome.
Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.
Nucleotide sequence of a cDNA coding for mitochondrial fumarase from human liver.
Systematic identification of post-transcriptional regulatory modules.
Mutation of the fumarase gene in two siblings with progressive encephalopathy and fumarase deficiency.
FH tetramer hydrates fumarate to L-malate
CLPXP binds mitochondrial matrix proteins
LONP1 degrades mitochondrial matrix proteins
LONP1 binds mitochondrial matrix proteins
CLPXP degrades mitochondrial matrix proteins
Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer.
Reversed argininosuccinate lyase activity in fumarate hydratase-deficient cancer cells.
HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stability.
Renal cyst formation in Fh1-deficient mice is independent of the Hif/Phd pathway: roles for fumarate in KEAP1 succination and Nrf2 signaling.
Comparative analysis of mitochondrial proteomes across the tree of life.
Author Correction: Local generation of fumarate promotes DNA repair through inhibition of histone H3 demethylation.
Author Correction: Systematic identification of post-transcriptional regulatory modules.
A role for cytosolic fumarate hydratase in urea cycle metabolism and renal neoplasia.