Gene Ontology annotation through association of InterPro records with GO terms

Gene Ontology annotation based on Enzyme Commission mapping

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Automatic Gene Ontology annotation based on Rhea mapping

Electronic Gene Ontology annotations created by ARBA machine learning models

Oligomerisation of Tube and Pelle leads to nuclear localisation of dorsal.

Formation and biochemical characterization of tube/pelle death domain complexes: critical regulators of postreceptor signaling by the Drosophila toll receptor.

Three-dimensional structure of a complex between the death domains of Pelle and Tube.

Toll-related receptors and the control of antimicrobial peptide expression in Drosophila.

Physical and functional interactions between Drosophila TRAF2 and Pelle kinase contribute to Dorsal activation.

Drosophila MyD88 is an adapter in the Toll signaling pathway.

Drosophila MyD88 is required for the response to fungal and Gram-positive bacterial infections.

Tehao functions in the Toll pathway in Drosophila melanogaster: possible roles in development and innate immunity.

A heterotrimeric death domain complex in Toll signaling.

Thicker than blood: conserved mechanisms in Drosophila and vertebrate hematopoiesis.

Endocytic pathway is required for Drosophila Toll innate immune signaling.

The IRAK homolog Pelle is the functional counterpart of IκB kinase in the Drosophila Toll pathway.

Toll Receptor-Mediated Hippo Signaling Controls Innate Immunity in Drosophila.

Information for the dorsal--ventral pattern of the Drosophila embryo is stored as maternal mRNA.

Interaction of the pelle kinase with the membrane-associated protein tube is required for transduction of the dorsoventral signal in Drosophila embryos.

Genetic characterization of tube and pelle, genes required for signaling between Toll and dorsal in the specification of the dorsal-ventral pattern of the Drosophila embryo.

pelle encodes a protein kinase required to establish dorsoventral polarity in the Drosophila embryo.

The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults.

Functional interactions between the pelle kinase, Toll receptor, and tube suggest a mechanism for activation of dorsal.

A gradient of cytoplasmic Cactus degradation establishes the nuclear localization gradient of the dorsal morphogen in Drosophila.

An activity-dependent network of interactions links the Rel protein Dorsal with its cytoplasmic regulators.

Recruitment of Tube and Pelle to signaling sites at the surface of the Drosophila embryo.

The Toll pathway is required in the epidermis for muscle development in the Drosophila embryo.

Phosphorylation modulates direct interactions between the Toll receptor, Pelle kinase and Tube.

Activated PLL kinase is autophosphorylated in TL:MYD88:TUB:PLL 'signalling complex'

PLL kinase binds to TL:MYD88:TUB 'signalling complex'

CACT and DL dimer are phosphorylated in TL:WEK:MYD88:TUB:PLL 'signalling complex'

Phosphorylated CACT and DL dimer dissociate from the TL:WEK:MYD88:TUB:PLL 'signalling complex'

DL/DIF dimer binds to TUB and phosphorylated PLL in TL:MYD88:TUB:PLL 'signalling complex'

Activated PLL kinase is autophosphorylated in TL:WEK:MYD88:TUB:PLL 'signalling complex'

CACT and DL/DIF dimer are phosphorylated in TL:MYD88:TUB:PLL 'signalling complex'

Phosphorylated CACT and DL/DIF dimer dissociate from the TL:MYD88:TUB:PLL 'signalling complex'

PLL kinase binds to TL:WEK:MYD88:TUB 'signalling complex'

DL dimer binds to TUB and phosphorylated PLL in TL:WEK:MYD88:TUB:PLL 'signalling complex'

Pelle Modulates dFoxO-Mediated Cell Death in Drosophila.

Maintaining Toll signaling in Drosophila brain is required to sustain autophagy for dopamine neuron survival.