The research report should be a detailed narrative explaining the function, biological processes, and localization of the gene product. Citations should be given for all claims.
You should prioritize authoritative reviews and primary scientific literature when conducting research. You can supplement
this with annotations you find in gene/protein databases, but these can be outdated or inaccurate.
We are specifically interested in the primary function of the gene - for enzymes, what reaction is catalyzed, and what is the substrate specificity? For transporters, what is the substrate? For structural proteins or adapters, what is the broader structural role? For signaling molecules, what is the role in the pathway.
We are interested in where in or outside the cell the gene product carries out its function.
We are also interested in the signaling or biochemical pathways in which the gene functions. We are less interested in broad pleiotropic effects, except where these elucidate the precise role.
Include evidence where possible. We are interested in both experimental evidence as well as inference from structure, evolution, or bioinformatic analysis. Precise studies should be prioritized over high-throughput, where available.
The requested protein is correctly identified as AtSUN1, the product of Arabidopsis thaliana locus At5g04990 and UniProt accession Q9FF75. It is a classical C-terminal SUN-domain protein and an integral component of the inner nuclear membrane (INM). This identity is distinct from mammalian SUN1, SUN proteins in rice or moss, and the Arabidopsis mid-SUN proteins SUN3–SUN5. Arabidopsis AtSUN2 is the close paralog encoded by At3g10730. AtSUN1 contains the expected SUN/LINC architecture—an N-terminal nucleoplasmic region with a nuclear-localization signal, a transmembrane/coiled-coil region, and a conserved C-terminal SUN domain exposed to the perinuclear lumen—consistent with the supplied InterPro/Pfam assignments SUN1–5, SUN_dom, and Sad1_UNC. (varas2015absenceofsun1 pages 4-8, zhou2012novelplantsun–kash pages 1-2)
AtSUN1 is not an enzyme or transporter. Its primary function is structural and mechanochemical: together with AtSUN2, it forms the inner-membrane half of plant LINC complexes that bridge nucleoplasmic/chromosomal structures to outer-nuclear-membrane KASH-like proteins and, through them, the cytoskeleton. Its best-supported functions are maintenance of nuclear architecture, anchoring of nuclear-envelope proteins, coordinated nuclear-envelope remodeling during mitosis, and—most decisively—attachment and movement of chromosomes at the nuclear envelope during meiosis. (varas2015absenceofsun1 pages 1-4, zhou2012novelplantsun–kash pages 3-4)
The central caveat is extensive functional redundancy with AtSUN2. AtSUN1 single mutants have no obvious fertility or meiotic phenotype, whereas combined SUN1/SUN2 disruption produces severe defects. Consequently, many physiological conclusions concern the SUN1/SUN2 module rather than an independently demonstrated SUN1-only activity. (varas2015absenceofsun1 pages 4-8, varas2015absenceofsun1 pages 8-12)
| Topic | Current conclusion | Strongest experimental evidence / method | Attribution | Key quantitative result |
|---|---|---|---|---|
| Identity and domain class | AtSUN1 is the Arabidopsis thaliana At5g04990 product (UniProt Q9FF75), a classical C-terminal SUN-domain nuclear-envelope protein distinct from AtSUN2 and mid-SUN3/4/5 proteins. | Locus mapping, sequence/domain analysis, mutant alleles, and protein localization | SUN1-specific identity; family classification shared with SUN2 | AtSUN1 = At5g04990; AtSUN2 = At3g10730 |
| Inner nuclear-membrane localization and topology | AtSUN1 is an integral inner nuclear-membrane protein with an N-terminal nucleoplasmic region, transmembrane/coiled-coil architecture, and a C-terminal SUN domain exposed to the perinuclear lumen. Its N-terminal and coiled-coil regions contribute to nuclear-envelope retention. | GFP-tagged genomic reporters, deletion mapping, confocal imaging, and INM-selective proximity proteomics | Primarily SUN1-specific; topology class conserved with SUN2 | SUN1-BioID2 identified 15 INM-selective proximal proteins at >2-fold enrichment and adjusted P < 0.05 |
| WIP/KASH LINC interaction | The lumenal SUN domain binds the C-terminal KASH-like motif of outer nuclear-membrane WIP proteins, forming a trans-envelope LINC bridge. | FRAP mobility-shift assays and domain deletions; supporting co-immunoprecipitation | Direct FRAP evidence for SUN1–WIP1; some biochemical validation used SUN2 | SUN1 reduced WIP1 mobility significantly (P < 0.01; n = 30); deleting either interaction motif abolished the effect |
| Nuclear shape and RanGAP anchoring | SUN1/2–WIP bridges maintain elongated nuclei and anchor RanGAP at the nuclear envelope; RanGAP association is mediated through WIP rather than demonstrated as direct SUN1 binding. | SUN1-knockout/SUN2-knockdown genetics, nuclear morphometry, fluorescence localization, and co-immunoprecipitation | Joint SUN1/SUN2 function; direct complex assay chiefly involved SUN2 | Nuclear-shape samples: 60 leaf, 20 trichome, and 55 root-hair nuclei; RanGAP localization: n = 55, P < 0.01 |
| Mitotic dynamics | AtSUN1 follows nuclear-envelope breakdown and reassembly; it first accumulates on the distal daughter-nuclear surface during telophase, with later proximal assembly coordinated with spindle remnants and the phragmoplast. | Live spinning-disk confocal imaging of AtSUN1 with chromosomes, ER, and microtubules; taxol perturbation | SUN1-specific imaging, with related behavior reported for SUN2 | Taxol-dependent distal/proximal reassembly analysis used six nuclei |
| Meiotic telomere attachment, bouquet, and rapid movements | SUN1/2-enriched envelope domains tether telomeres, establish the peripheral bouquet, support nucleolar displacement, and transmit forces required for rapid meiotic chromosome movements. | Live meiocyte imaging, SUN/NUP reporters, centromere tracking, telomere FISH, and sun1 sun2 genetics | Joint, redundant SUN1/SUN2 function; not assignable to SUN1 alone | Wild-type centromeres averaged about 100 nm/s and reached 500 nm/s; double-mutant average was 54 ± 2 nm/s (n = 65 tracks), with diffusion coefficient 0.002 µm²/s |
| Bouquet organization | Loss of both proteins shifts telomeres from the nuclear envelope into nucleoplasmic clusters near the nucleolus and disrupts normal nuclear polarity. | Three-dimensional telomere imaging and stage-resolved cytology | Joint SUN1/SUN2 function | Peripheral telomeres: 93% in wild type versus 40% in the double mutant; 20/22 mutant cells had nucleoplasmic clusters averaging 8.5 telomeres |
| Recombination and fertility | SUN1 and SUN2 redundantly promote stable homolog pairing, synapsis, crossover maturation, balanced segregation, and fertility. Single mutants show no obvious meiotic defect, whereas combined loss is severe. | Double-mutant cytology, EdU meiotic timing, synaptonemal-complex measurements, recombination-marker counts, and seed-set assays | Joint SUN1/SUN2 function; no detectable SUN1-only phenotype | Seeds per silique fell from 60.4 ± 2.5 to 2.1 ± 0.9; chiasmata from 10.2 ± 0.14 to 3.32 ± 0.18; synapsis averaged 50.71%; meiosis was delayed about 12 h |
| Inner nuclear-membrane proteostasis | AtSUN1 undergoes constitutive ubiquitin–proteasome-dependent turnover and lies near CDC48–UFD1–NPL4 and PUX3/4/5 machinery; PUX proteins appear to restrain rather than promote its degradation. | SUN1-BioID2 proteomics, cycloheximide chase, MG132 and autophagy inhibition, co-immunoprecipitation, and pux mutant analysis | SUN1-specific bait and turnover assays | In the pux3 pux4 pux5 mutant, SUN1 declined by nearly 70% within 4 h; MG132 blocked turnover |
Table: A concise evidence matrix distinguishing AtSUN1-specific findings from phenotypes demonstrated only after combined SUN1/SUN2 disruption. It summarizes molecular architecture, cellular roles, experimental approaches, and the principal quantitative results.
The literature explicitly maps AtSUN1 to At5g04990 and distinguishes it from AtSUN2/At3g10730. AtSUN1 and AtSUN2 are the two Arabidopsis classical C-terminal SUN proteins, whereas SUN3, SUN4, and SUN5 are topologically different mid-SUN proteins with important ER-associated functions. The SUN1 designation is therefore genuinely ambiguous across organisms, but the Arabidopsis locus, accession, and domain architecture supplied in the question agree with the target-specific literature. (varas2015absenceofsun1 pages 4-8, fernandezjimenez2020theroleof pages 13-14)
AtSUN1 is an integral INM protein. Its N-terminal region faces the nucleoplasm, while the conserved C-terminal SUN domain occupies the nuclear-envelope lumen/perinuclear space, where it can bind the short lumenal KASH-like tails of outer-nuclear-membrane proteins. Coiled-coil-mediated oligomerization and SUN1–SUN2 homo-/heteromeric association are thought to strengthen this bridge. (varas2015absenceofsun1 pages 4-8, varas2015absenceofsun1 pages 1-4)
Fluorescent-protein reporters localized AtSUN1 to the chromatin/nuclear periphery in roots, hypocotyls, cotyledons, leaves, meristematic cells, epidermal cells, and root hairs. Deletion experiments showed that the N-terminal sequence, transmembrane segment, and coiled-coil region contribute to INM targeting or retention; deleting the SUN domain did not by itself abolish nuclear-envelope localization. Thus, the SUN domain primarily mediates partner binding rather than serving as the sole targeting signal. (oda2011dynamicsofarabidopsis pages 2-3)
The core LINC arrangement is:
nucleoplasm/chromatin or nucleoskeleton → AtSUN1/AtSUN2 in the INM → WIP/SINE KASH-like proteins in the outer nuclear membrane → cytoskeletal or motor-associated components.
Direct FRAP-based evidence showed that AtSUN1 significantly reduced the mobility of AtWIP1 at the nuclear envelope. Removing the SUN interaction region from AtSUN1 or the C-terminal VVPT KASH-like motif from WIP1 abolished this effect (P<0.01; n=30), demonstrating motif-dependent membrane interaction rather than simple colocalization. Some complementary co-immunoprecipitation assays used AtSUN2, so the strongest biochemical complex evidence cannot always be assigned uniquely to AtSUN1. (zhou2012novelplantsun–kash pages 3-4)
Arabidopsis LINC bridges can connect to actin through SINE1 or through a WIP–WIT–myosin XI-I assembly. AtSUN1 should therefore be viewed as an INM force-transmission adaptor: it does not itself hydrolyze ATP or generate motion, but couples nuclear or chromosomal structures to cytoplasmic force-generating systems. (varas2015absenceofsun1 pages 4-8)
Joint depletion of SUN1 and SUN2 makes normally elongated leaf epidermal, trichome, and root-hair nuclei more rounded. The relevant morphometric analyses examined 60 epidermal, 20 trichome, and 55 root-hair nuclei and found significant differences (P<0.01). Because the experiments combined SUN1 knockout with SUN2 knockdown, they establish a redundant SUN-module function rather than a unique SUN1 requirement. (zhou2012novelplantsun–kash pages 5-6)
SUN–WIP bridges also retain RanGAP at the nuclear envelope. In sun1-KO sun2-KD roots, AtWIP1 and AtRanGAP1 became significantly less concentrated at the nuclear periphery; RanGAP localization was quantified across n=55 cells (P<0.01). RanGAP binds WIP, which in turn binds SUN, so RanGAP anchoring is indirect with respect to AtSUN1. (zhou2012novelplantsun–kash pages 4-5, zhou2012novelplantsun–kash pages 5-6)
Live spinning-disk confocal microscopy showed that AtSUN1 follows nuclear-envelope breakdown and reformation. During telophase it first accumulated on the distal surface of daughter nuclei and subsequently on the proximal surface. This asymmetric reassembly was spatially and temporally coordinated with spindle remnants and phragmoplast microtubules; taxol delayed proximal AtSUN1 accumulation. These observations support a role in rebuilding a polarized, mechanically organized envelope after open mitosis, although they do not establish AtSUN1 as the initiating factor. (oda2011dynamicsofarabidopsis pages 1-2, oda2011dynamicsofarabidopsis pages 5-7)
During early meiotic prophase I, AtSUN1 and AtSUN2 redistribute from a relatively uniform nuclear-envelope pattern into polarized SUN-enriched domains. Chromosome ends associate with these domains, telomeres form the peripheral “bouquet,” and cytoskeletal forces drive rapid chromosome motion. The resulting movements facilitate productive homologue encounters, synapsis, interlock resolution, and crossover maturation. At diplotene, the SUN distribution becomes more broadly peripheral again. (cromer2024rapidmeioticprophase pages 9-10, cromer2024rapidmeioticprophase pages 7-9)
The major recent advance is Cromer et al., published July 2024 in Nature Communications (DOI/URL). Live imaging showed uncoordinated centromere movements during zygotene and pachytene, averaging approximately 100 nm/s and reaching 500 nm/s. These movements persisted in several mutants affecting chromosome organization or recombination but were essentially abolished as directed rapid movements in the sun1 sun2 double mutant. Mutant tracks averaged 54 ± 2 nm/s across 65 tracks and had a diffusion coefficient of only 0.002 µm²/s, resembling largely stationary or back-and-forth somatic movement. (cromer2024rapidmeioticprophase pages 1-2, cromer2024rapidmeioticprophase pages 10-12, cromer2024rapidmeioticprophase pages 6-7)
SUN polarization was systematic at zygotene (13/13 cells), and SUN-rich clumps frequently corresponded to anchored chromosome ends. In wild type, approximately 93% of telomeres were peripheral and a clear peripheral bouquet was present in 95% of zygotene/pachytene cells. In the double mutant, only about 40% of telomeres remained peripheral; 20/22 cells instead contained nucleoplasmic clusters averaging 8.5 telomeres near the nucleolus. Normal movement of the nucleolus toward the nuclear periphery was also disrupted. (cromer2024rapidmeioticprophase pages 9-10, cromer2024rapidmeioticprophase pages 10-12)
These results establish that the SUN1/SUN2 module is upstream of telomere-led rapid chromosome movement and nuclear polarization. They do not demonstrate that SUN1 alone is indispensable, because SUN2 can compensate in single mutants. Residual telomere attachment in the double mutant may indicate partial compensation by another INM component. (cromer2024rapidmeioticprophase pages 14-15)
Varas et al., published January 2015 in The Plant Journal (DOI/URL), showed that complete combined loss of AtSUN1 and AtSUN2 causes a severe but mechanistically informative phenotype:
The double mutant produced univalents, rod bivalents, persistent interlock-like structures, lagging chromosomes, and unbalanced meiotic products. These observations support a causal sequence in which unstable telomere–envelope attachment impairs chromosome motion, which then reduces stable homologue pairing and synapsis, leaving fewer sites competent for MLH1-marked crossovers and balanced segregation. (varas2015absenceofsun1 pages 19-22, varas2015absenceofsun1 pages 45-54)
Huang et al., published June 2020 in Nature Communications (DOI/URL), used AtSUN1–BioID2 as an INM bait. Relative to outer-membrane WIT1 and mock controls, 15 proteins met the SUN1-selective threshold of greater than twofold enrichment and adjusted P<0.05. These included CRWN1–CRWN4 and KAKU4, supporting spatial coupling between SUN1 and the plant nucleoskeleton, as well as UFD1 and PUX proteins associated with the CDC48 extraction machinery. BioID establishes proximity, not necessarily direct binding. (huang2020proximitylabelingproteomics pages 1-2, huang2020proximitylabelingproteomics pages 2-3)
Cycloheximide-chase and inhibitor experiments showed that AtSUN1 undergoes constitutive, ubiquitin/proteasome-dependent turnover: MG132 stabilized and increased polyubiquitinated SUN1, whereas autophagy inhibition did not. SUN1 associated biochemically with PUX4 and PUX5, although cellular interaction signals were weak and may represent transient or indirect contacts. Unexpectedly, loss of PUX3/4/5 accelerated SUN1 turnover—nearly 70% loss within four hours—suggesting that these factors restrain CDC48-dependent extraction or otherwise protect INM proteins rather than simply recruiting them for destruction. The responsible ubiquitin ligase and exact extraction sequence remain unknown. (huang2020proximitylabelingproteomics pages 3-4, huang2020proximitylabelingproteomics pages 5-6, huang2020proximitylabelingproteomics pages 6-8)
The most important target-specific development in 2023–2024 is the 2024 direct visualization and quantification of SUN1/SUN2-dependent rapid meiotic chromosome movements. It converted the earlier inference—derived from bouquet, synapsis, and recombination defects—into a measured mechanochemical function and showed that the nuclear envelope itself undergoes stage-specific reorganization. (cromer2024rapidmeioticprophase pages 9-10, cromer2024rapidmeioticprophase pages 1-2)
A February 2023 authoritative review in Nucleus (DOI/URL) framed the plant nuclear envelope as an active hub for chromatin organization and gene regulation rather than a passive boundary. In that framework, SUN proteins are force-transmitting and genome-organizing components, but direct evidence that AtSUN1 controls specific transcriptional loci remains substantially weaker than the evidence for nuclear mechanics and meiosis. (tang2023plantnuclearenvelope pages 13-14)
A separate 2023 study of Arabidopsis mid-SUN proteins concerned SUN3/SUN4 and ER topology, not Q9FF75/AtSUN1. It should not be used to assign ER cargo-sorting or receptor-kinase chaperone functions to AtSUN1. This distinction is essential because the shared “SUN” nomenclature covers topologically and functionally different Arabidopsis subfamilies.
At present, AtSUN1 has research applications rather than a deployed agricultural use:
The most defensible functional annotation is:
AtSUN1 is an inner nuclear-membrane mechanochemical adaptor that, largely redundantly with AtSUN2, forms SUN–KASH-like LINC bridges coupling the plant nucleoskeleton and meiotic chromosome ends to outer-membrane/cytoskeletal machinery. It maintains nuclear architecture and enables telomere attachment, bouquet formation, rapid prophase chromosome movement, homologous synapsis, crossover maturation, and balanced meiotic segregation.
This interpretation is supported by convergent localization, deletion mapping, FRAP interaction assays, live-cell microscopy, genetics, cytology, and proximity proteomics. It is stronger than broad annotations such as “nuclear organization” because it specifies the molecular bridge, membrane compartment, and force-transmission role. (zhou2012novelplantsun–kash pages 3-4, cromer2024rapidmeioticprophase pages 1-2)
Important limitations remain. Most organismal phenotypes require combined SUN1/SUN2 loss, so paralog-specific contributions are unresolved. The cytoplasmic motor responsible for Arabidopsis meiotic motion was not established by the 2024 study. Direct nucleoplasmic tethers connecting SUN1 to telomeres/chromatin remain incompletely defined, and BioID proximity to CRWN proteins does not prove stable direct binding. Finally, the relationship between SUN1-dependent mechanics and transcriptional regulation is plausible but less directly demonstrated than its meiotic and structural functions. (cromer2024rapidmeioticprophase pages 14-15, huang2020proximitylabelingproteomics pages 3-4)
References
(varas2015absenceofsun1 pages 4-8): Javier Varas, Katja Graumann, Kim Osman, Mónica Pradillo, David E. Evans, Juan L. Santos, and Susan J. Armstrong. Absence of sun1 and sun2 proteins in arabidopsis thaliana leads to a delay in meiotic progression and defects in synapsis and recombination. The Plant journal : for cell and molecular biology, 81 2:329-46, Jan 2015. URL: https://doi.org/10.1111/tpj.12730, doi:10.1111/tpj.12730. This article has 123 citations.
(zhou2012novelplantsun–kash pages 1-2): Xiao Zhou, Katja Graumann, David E. Evans, and Iris Meier. Novel plant sun–kash bridges are involved in rangap anchoring and nuclear shape determination. The Journal of Cell Biology, 196:203-211, Jan 2012. URL: https://doi.org/10.1083/jcb.201108098, doi:10.1083/jcb.201108098. This article has 188 citations.
(varas2015absenceofsun1 pages 1-4): Javier Varas, Katja Graumann, Kim Osman, Mónica Pradillo, David E. Evans, Juan L. Santos, and Susan J. Armstrong. Absence of sun1 and sun2 proteins in arabidopsis thaliana leads to a delay in meiotic progression and defects in synapsis and recombination. The Plant journal : for cell and molecular biology, 81 2:329-46, Jan 2015. URL: https://doi.org/10.1111/tpj.12730, doi:10.1111/tpj.12730. This article has 123 citations.
(zhou2012novelplantsun–kash pages 3-4): Xiao Zhou, Katja Graumann, David E. Evans, and Iris Meier. Novel plant sun–kash bridges are involved in rangap anchoring and nuclear shape determination. The Journal of Cell Biology, 196:203-211, Jan 2012. URL: https://doi.org/10.1083/jcb.201108098, doi:10.1083/jcb.201108098. This article has 188 citations.
(varas2015absenceofsun1 pages 8-12): Javier Varas, Katja Graumann, Kim Osman, Mónica Pradillo, David E. Evans, Juan L. Santos, and Susan J. Armstrong. Absence of sun1 and sun2 proteins in arabidopsis thaliana leads to a delay in meiotic progression and defects in synapsis and recombination. The Plant journal : for cell and molecular biology, 81 2:329-46, Jan 2015. URL: https://doi.org/10.1111/tpj.12730, doi:10.1111/tpj.12730. This article has 123 citations.
(fernandezjimenez2020theroleof pages 13-14): Nadia Fernández-Jiménez and Mónica Pradillo. The role of the nuclear envelope in the regulation of chromatin dynamics during cell division. Journal of experimental botany, 71:5148-5159, Jun 2020. URL: https://doi.org/10.1093/jxb/eraa299, doi:10.1093/jxb/eraa299. This article has 13 citations and is from a domain leading peer-reviewed journal.
(oda2011dynamicsofarabidopsis pages 2-3): Yoshihisa Oda and Hiroo Fukuda. Dynamics of arabidopsis sun proteins during mitosis and their involvement in nuclear shaping. The Plant journal : for cell and molecular biology, 66 4:629-41, May 2011. URL: https://doi.org/10.1111/j.1365-313x.2011.04523.x, doi:10.1111/j.1365-313x.2011.04523.x. This article has 155 citations.
(zhou2012novelplantsun–kash pages 5-6): Xiao Zhou, Katja Graumann, David E. Evans, and Iris Meier. Novel plant sun–kash bridges are involved in rangap anchoring and nuclear shape determination. The Journal of Cell Biology, 196:203-211, Jan 2012. URL: https://doi.org/10.1083/jcb.201108098, doi:10.1083/jcb.201108098. This article has 188 citations.
(zhou2012novelplantsun–kash pages 4-5): Xiao Zhou, Katja Graumann, David E. Evans, and Iris Meier. Novel plant sun–kash bridges are involved in rangap anchoring and nuclear shape determination. The Journal of Cell Biology, 196:203-211, Jan 2012. URL: https://doi.org/10.1083/jcb.201108098, doi:10.1083/jcb.201108098. This article has 188 citations.
(oda2011dynamicsofarabidopsis pages 1-2): Yoshihisa Oda and Hiroo Fukuda. Dynamics of arabidopsis sun proteins during mitosis and their involvement in nuclear shaping. The Plant journal : for cell and molecular biology, 66 4:629-41, May 2011. URL: https://doi.org/10.1111/j.1365-313x.2011.04523.x, doi:10.1111/j.1365-313x.2011.04523.x. This article has 155 citations.
(oda2011dynamicsofarabidopsis pages 5-7): Yoshihisa Oda and Hiroo Fukuda. Dynamics of arabidopsis sun proteins during mitosis and their involvement in nuclear shaping. The Plant journal : for cell and molecular biology, 66 4:629-41, May 2011. URL: https://doi.org/10.1111/j.1365-313x.2011.04523.x, doi:10.1111/j.1365-313x.2011.04523.x. This article has 155 citations.
(cromer2024rapidmeioticprophase pages 9-10): Laurence Cromer, Mariana Tiscareno-Andrade, Sandrine Lefranc, Aurélie Chambon, Aurélie Hurel, Manon Brogniez, Julie Guérin, Ivan Le Masson, Gabriele Adam, Delphine Charif, Philippe Andrey, and Mathilde Grelon. Rapid meiotic prophase chromosome movements in arabidopsis thaliana are linked to essential reorganization at the nuclear envelope. Nature Communications, Jul 2024. URL: https://doi.org/10.1038/s41467-024-50169-4, doi:10.1038/s41467-024-50169-4. This article has 25 citations and is from a highest quality peer-reviewed journal.
(cromer2024rapidmeioticprophase pages 7-9): Laurence Cromer, Mariana Tiscareno-Andrade, Sandrine Lefranc, Aurélie Chambon, Aurélie Hurel, Manon Brogniez, Julie Guérin, Ivan Le Masson, Gabriele Adam, Delphine Charif, Philippe Andrey, and Mathilde Grelon. Rapid meiotic prophase chromosome movements in arabidopsis thaliana are linked to essential reorganization at the nuclear envelope. Nature Communications, Jul 2024. URL: https://doi.org/10.1038/s41467-024-50169-4, doi:10.1038/s41467-024-50169-4. This article has 25 citations and is from a highest quality peer-reviewed journal.
(cromer2024rapidmeioticprophase pages 1-2): Laurence Cromer, Mariana Tiscareno-Andrade, Sandrine Lefranc, Aurélie Chambon, Aurélie Hurel, Manon Brogniez, Julie Guérin, Ivan Le Masson, Gabriele Adam, Delphine Charif, Philippe Andrey, and Mathilde Grelon. Rapid meiotic prophase chromosome movements in arabidopsis thaliana are linked to essential reorganization at the nuclear envelope. Nature Communications, Jul 2024. URL: https://doi.org/10.1038/s41467-024-50169-4, doi:10.1038/s41467-024-50169-4. This article has 25 citations and is from a highest quality peer-reviewed journal.
(cromer2024rapidmeioticprophase pages 10-12): Laurence Cromer, Mariana Tiscareno-Andrade, Sandrine Lefranc, Aurélie Chambon, Aurélie Hurel, Manon Brogniez, Julie Guérin, Ivan Le Masson, Gabriele Adam, Delphine Charif, Philippe Andrey, and Mathilde Grelon. Rapid meiotic prophase chromosome movements in arabidopsis thaliana are linked to essential reorganization at the nuclear envelope. Nature Communications, Jul 2024. URL: https://doi.org/10.1038/s41467-024-50169-4, doi:10.1038/s41467-024-50169-4. This article has 25 citations and is from a highest quality peer-reviewed journal.
(cromer2024rapidmeioticprophase pages 6-7): Laurence Cromer, Mariana Tiscareno-Andrade, Sandrine Lefranc, Aurélie Chambon, Aurélie Hurel, Manon Brogniez, Julie Guérin, Ivan Le Masson, Gabriele Adam, Delphine Charif, Philippe Andrey, and Mathilde Grelon. Rapid meiotic prophase chromosome movements in arabidopsis thaliana are linked to essential reorganization at the nuclear envelope. Nature Communications, Jul 2024. URL: https://doi.org/10.1038/s41467-024-50169-4, doi:10.1038/s41467-024-50169-4. This article has 25 citations and is from a highest quality peer-reviewed journal.
(cromer2024rapidmeioticprophase pages 14-15): Laurence Cromer, Mariana Tiscareno-Andrade, Sandrine Lefranc, Aurélie Chambon, Aurélie Hurel, Manon Brogniez, Julie Guérin, Ivan Le Masson, Gabriele Adam, Delphine Charif, Philippe Andrey, and Mathilde Grelon. Rapid meiotic prophase chromosome movements in arabidopsis thaliana are linked to essential reorganization at the nuclear envelope. Nature Communications, Jul 2024. URL: https://doi.org/10.1038/s41467-024-50169-4, doi:10.1038/s41467-024-50169-4. This article has 25 citations and is from a highest quality peer-reviewed journal.
(varas2015absenceofsun1 pages 41-45): Javier Varas, Katja Graumann, Kim Osman, Mónica Pradillo, David E. Evans, Juan L. Santos, and Susan J. Armstrong. Absence of sun1 and sun2 proteins in arabidopsis thaliana leads to a delay in meiotic progression and defects in synapsis and recombination. The Plant journal : for cell and molecular biology, 81 2:329-46, Jan 2015. URL: https://doi.org/10.1111/tpj.12730, doi:10.1111/tpj.12730. This article has 123 citations.
(varas2015absenceofsun1 pages 15-19): Javier Varas, Katja Graumann, Kim Osman, Mónica Pradillo, David E. Evans, Juan L. Santos, and Susan J. Armstrong. Absence of sun1 and sun2 proteins in arabidopsis thaliana leads to a delay in meiotic progression and defects in synapsis and recombination. The Plant journal : for cell and molecular biology, 81 2:329-46, Jan 2015. URL: https://doi.org/10.1111/tpj.12730, doi:10.1111/tpj.12730. This article has 123 citations.
(varas2015absenceofsun1 pages 12-15): Javier Varas, Katja Graumann, Kim Osman, Mónica Pradillo, David E. Evans, Juan L. Santos, and Susan J. Armstrong. Absence of sun1 and sun2 proteins in arabidopsis thaliana leads to a delay in meiotic progression and defects in synapsis and recombination. The Plant journal : for cell and molecular biology, 81 2:329-46, Jan 2015. URL: https://doi.org/10.1111/tpj.12730, doi:10.1111/tpj.12730. This article has 123 citations.
(varas2015absenceofsun1 pages 19-22): Javier Varas, Katja Graumann, Kim Osman, Mónica Pradillo, David E. Evans, Juan L. Santos, and Susan J. Armstrong. Absence of sun1 and sun2 proteins in arabidopsis thaliana leads to a delay in meiotic progression and defects in synapsis and recombination. The Plant journal : for cell and molecular biology, 81 2:329-46, Jan 2015. URL: https://doi.org/10.1111/tpj.12730, doi:10.1111/tpj.12730. This article has 123 citations.
(varas2015absenceofsun1 pages 45-54): Javier Varas, Katja Graumann, Kim Osman, Mónica Pradillo, David E. Evans, Juan L. Santos, and Susan J. Armstrong. Absence of sun1 and sun2 proteins in arabidopsis thaliana leads to a delay in meiotic progression and defects in synapsis and recombination. The Plant journal : for cell and molecular biology, 81 2:329-46, Jan 2015. URL: https://doi.org/10.1111/tpj.12730, doi:10.1111/tpj.12730. This article has 123 citations.
(huang2020proximitylabelingproteomics pages 1-2): Aobo Huang, Yu Tang, Xuetao Shi, Min Jia, Jinheng Zhu, Xiaohan Yan, Huiqin Chen, and Yangnan Gu. Proximity labeling proteomics reveals critical regulators for inner nuclear membrane protein degradation in plants. Nature Communications, Jun 2020. URL: https://doi.org/10.1038/s41467-020-16744-1, doi:10.1038/s41467-020-16744-1. This article has 80 citations and is from a highest quality peer-reviewed journal.
(huang2020proximitylabelingproteomics pages 2-3): Aobo Huang, Yu Tang, Xuetao Shi, Min Jia, Jinheng Zhu, Xiaohan Yan, Huiqin Chen, and Yangnan Gu. Proximity labeling proteomics reveals critical regulators for inner nuclear membrane protein degradation in plants. Nature Communications, Jun 2020. URL: https://doi.org/10.1038/s41467-020-16744-1, doi:10.1038/s41467-020-16744-1. This article has 80 citations and is from a highest quality peer-reviewed journal.
(huang2020proximitylabelingproteomics pages 3-4): Aobo Huang, Yu Tang, Xuetao Shi, Min Jia, Jinheng Zhu, Xiaohan Yan, Huiqin Chen, and Yangnan Gu. Proximity labeling proteomics reveals critical regulators for inner nuclear membrane protein degradation in plants. Nature Communications, Jun 2020. URL: https://doi.org/10.1038/s41467-020-16744-1, doi:10.1038/s41467-020-16744-1. This article has 80 citations and is from a highest quality peer-reviewed journal.
(huang2020proximitylabelingproteomics pages 5-6): Aobo Huang, Yu Tang, Xuetao Shi, Min Jia, Jinheng Zhu, Xiaohan Yan, Huiqin Chen, and Yangnan Gu. Proximity labeling proteomics reveals critical regulators for inner nuclear membrane protein degradation in plants. Nature Communications, Jun 2020. URL: https://doi.org/10.1038/s41467-020-16744-1, doi:10.1038/s41467-020-16744-1. This article has 80 citations and is from a highest quality peer-reviewed journal.
(huang2020proximitylabelingproteomics pages 6-8): Aobo Huang, Yu Tang, Xuetao Shi, Min Jia, Jinheng Zhu, Xiaohan Yan, Huiqin Chen, and Yangnan Gu. Proximity labeling proteomics reveals critical regulators for inner nuclear membrane protein degradation in plants. Nature Communications, Jun 2020. URL: https://doi.org/10.1038/s41467-020-16744-1, doi:10.1038/s41467-020-16744-1. This article has 80 citations and is from a highest quality peer-reviewed journal.
(tang2023plantnuclearenvelope pages 13-14): Yu Tang. Plant nuclear envelope as a hub connecting genome organization with regulation of gene expression. Nucleus, Feb 2023. URL: https://doi.org/10.1080/19491034.2023.2178201, doi:10.1080/19491034.2023.2178201. This article has 14 citations and is from a peer-reviewed journal.