InterPro IPR001872 identifies LspA as a peptidase A8 membrane protease, but the broad proteolysis and membrane terms need refinement in review.

Combined UniProt automated evidence supplies the aspartic-type endopeptidase and plasma membrane annotations for LspA.

UniProt/HAMAP identifies Q88Q91 as lipoprotein signal peptidase II, EC 3.4.23.36, in the lipoprotein biosynthesis signal-peptide cleavage pathway, with multi-pass inner-membrane localization and two aspartate active-site residues.

The fetched GOA table contains the four existing annotations reviewed for lspA.

PANTHER places LspA in the lipoprotein signal peptidase family, consistent with the peptidase A8/InterPro IPR001872 assignment.

OpenScientist supports LspA as the inner-membrane signal peptidase II step between Lgt and Lnt in bacterial lipoprotein maturation and notes that direct KT2440-specific biochemical characterization is still inferential from conserved orthologs.