Chromosomal localization of genes encoding guanine nucleotide-binding protein subunits in mouse and human.
Distinct forms of the beta subunit of GTP-binding regulatory proteins identified by molecular cloning.
A second form of the beta subunit of signal-transducing G proteins.
Mitogen-activated protein kinase activation requires two signal inputs from the human anaphylatoxin C5a receptor.
Large-scale sequencing of two regions in human chromosome 7q22: analysis of 650 kb of genomic sequence around the EPO and CUTL1 loci reveals 17 genes.
The git5 Gbeta and git11 Ggamma form an atypical Gbetagamma dimer acting in the fission yeast glucose/cAMP pathway.
The DNA sequence of human chromosome 7.
G Protein betagamma subunits stimulate p114RhoGEF, a guanine nucleotide exchange factor for RhoA and Rac1: regulation of cell shape and reactive oxygen species production.
Complete sequencing and characterization of 21,243 full-length human cDNAs.
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Ataxin 10 induces neuritogenesis via interaction with G-protein beta2 subunit.
Human colostrum: identification of minor proteins in the aqueous phase by proteomics.
Huntingtin interacting proteins are genetic modifiers of neurodegeneration.
Integral and associated lysosomal membrane proteins.
Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense.
Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
The cationic region of Rhes mediates its interactions with specific Gbeta subunits.
Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
Defining the membrane proteome of NK cells.
Activated alleles of the Schizosaccharomyces pombe gpa2+ Galpha gene identify residues involved in GDP-GTP exchange.
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
Initial characterization of the human central proteome.
Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation.
KIF14 negatively regulates Rap1a-Radil signaling during breast cancer progression.
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
N-terminome analysis of the human mitochondrial proteome.
Pathogenic mechanism of recurrent mutations of SCN8A in epileptic encephalopathy.
A Mutation in the G-Protein Gene GNB2 Causes Familial Sinus Node and Atrioventricular Conduction Dysfunction.
Architecture of the human interactome defines protein communities and disease networks.
A Proteomic Variant Approach (ProVarA) for Personalized Medicine of Inherited and Somatic Disease.
Structures of the Rhodopsin-Transducin Complex: Insights into G-Protein Activation.
Inhibition of calpain 1 restores plasma membrane stability to pharmacologically rescued Phe508del-CFTR variant.
Exome reports A de novo GNB2 variant associated with global developmental delay, intellectual disability, and dysmorphic features.
Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.
Second patient with GNB2-related neurodevelopmental disease: Further evidence for a gene-disease association.
Recurrent de novo missense variants in GNB2 can cause syndromic intellectual disability.
Specificities of Gβγ subunits for the SNARE complex before and after stimulation of α(2a)-adrenergic receptors.
CFTR interactome mapping using the mammalian membrane two-hybrid high-throughput screening system.
Differential CFTR-Interactome Proximity Labeling Procedures Identify Enrichment in Multiple SLC Transporters.
Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Gene Ontology annotation based on curation of immunofluorescence data
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
TRiC/CCT binds unfolded G-protein beta subunit
ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT
PDCL binds G-protein beta and TRiC/CCT
ATP binds G-protein beta associated TRiC/CCT
PDCL promotes formation of G-beta:G-gamma heterodimers
Glucagon:GCGR mediates GTP-GDP exchange
PDCL releases folded G-beta from TRiC/CCT
G-protein alpha releases G-protein heterotrimer from PDCL
GNB2 source, product, phylogeny and assay evidence