Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on curation of immunofluorescence data
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Gene Ontology annotation of human sequence-specific DNA binding transcription factors (DbTFs) based on the TFClass database
Combined Automated Annotation using Multiple IEA Methods
A family of AP-2 proteins down-regulate manganese superoxide dismutase expression.
Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator.
Transcription factor AP-2 interacts with the SUMO-conjugating enzyme UBC9 and is sumolated in vivo.
Physical and functional interactions among AP-2 transcription factors, p300/CREB-binding protein, and CITED2.
Developmental changes in human fetal testicular cell numbers and messenger ribonucleic acid levels during the second trimester.
The interaction of KCTD1 with transcription factor AP-2alpha inhibits its transactivation.
CITED2 mutation links congenital heart defects to dysregulation of the cardiac gene VEGF and PITX2C expression.
Differential regulation of estrogen receptor α expression in breast cancer cells by metastasis-associated protein 1.
Sumoylation pathway is required to maintain the basal breast cancer subtype.
Impact of cytosine methylation on DNA binding specificities of human transcription factors.
Identification of ERF-1 as a member of the AP2 transcription factor family.
SUMOylation of TFAP2C with SUMO1
AP-2 (TFAP2) transcription factors form homo- and heterodimers
TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP
KCTD1 binds TFAP2 homo- and heterodimers
TFAP2A,TFAP2C homodimers bind ESR1 promoter
TFAP2A,TFAP2C homodimers bind the CGA gene
TFAP2A,TFAP2C homodimers bind the CGB gene promoter
TFAP2C translocates to the nucleus
TFAP2A,TFAP2C homodimers:CITED2 binds PITX2 gene promoter
TFAP2C homodimer binds MYC and KDM5B
TFAP2C homodimer binds the CDKN1A (p21) gene promoter
TFAP2C homodimer binds the EGFR gene promoter
SOX17 and TFAP2C bind the CBFA2T2 gene
Expression of TFAP2C in primordial germ cells
SOX17 and TFAP2C bind the TFAP2C gene
SOX17 and TFAP2C bind the PRDM1 gene
SOX17 and TFAP2C bind the NANOG gene
SOX17, TFAP2C, and PRDM1 (BLIMP1) bind the NANOS3 gene
SOX17 and TFAP2C bind the POU5F1 (OCT4) gene
Heterodimerization of TFAP2 pioneer factors drives epigenomic remodeling during neural crest specification.
Redundant activities of Tfap2a and Tfap2c are required for neural crest induction and development of other non-neural ectoderm derivatives in zebrafish embryos.
Human Primordial Germ Cells Are Specified from Lineage-Primed Progenitors.
The TFAP2C-Regulated OCT4 Naive Enhancer Is Involved in Human Germline Formation.
GATA transcription factors, SOX17 and TFAP2C, drive the human germ-cell specification program.
Critical function of AP-2 gamma/TCFAP2C in mouse embryonic germ cell maintenance.
Lineage regulators TFAP2C and NR5A2 function as bipotency activators in totipotent embryos.
Tpbpa-Cre-mediated deletion of TFAP2C leads to deregulation of Cdkn1a, Akt1 and the ERK pathway, causing placental growth arrest.
The transcriptional regulatory network modulating human trophoblast stem cells to extravillous trophoblast differentiation.
Identification of primary gene targets of TFAP2C in hormone responsive breast carcinoma cells.
AP-2 factors act in concert with Notch to orchestrate terminal differentiation in skin epidermis.
AP2gamma regulates basal progenitor fate in a region- and layer-specific manner in the developing cortex.