Gene Ontology annotation through association of InterPro records with GO terms

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Electronic Gene Ontology annotations created by ARBA machine learning models

Combined Automated Annotation using Multiple IEA Methods

Nogo-B receptor stabilizes Niemann-Pick type C2 protein and regulates intracellular cholesterol trafficking.

Nogo-B receptor is necessary for cellular dolichol biosynthesis and protein N-glycosylation.

Mutation of Nogo-B receptor, a subunit of cis-prenyltransferase, causes a congenital disorder of glycosylation.

Endothelial miR-26a regulates VEGF-Nogo-B receptor-mediated angiogenesis.

A conserved C-terminal RXG motif in the NgBR subunit of cis-prenyltransferase is critical for prenyltransferase activity.

Structural elucidation of the cis-prenyltransferase NgBR/DHDDS complex reveals insights in regulation of protein glycosylation.

Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.

DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP

Defective DHDDS does not elongate E,E-FPP