CIT1 (YNR001C, P00890) notes

• Acetyl-CoA-specific mitochondrial citrate synthase [PMID:17570335 "that of the CIT1 gene as a specific citrate synthase"; "Recombinant Cit1p had catalytic activity only with acetyl-CoA"].
• Deletion: impaired respiration of citrate/isocitrate, no growth on acetate PMID:2661555.
• Ser462 phosphorylation blocks dimerisation/activity; Ptc7p reverses PMID:28076776.
• Found in a mitochondrial dehydrogenase supercomplex PMID:11502169.
• Matrix [UniProt:P00890 "SUBCELLULAR LOCATION: Mitochondrion matrix"].

Curation: Reactome import-reaction IMS/cytosol rows and YeastCyc superpathway cytosol row removed (paralog CIT2 is the extramitochondrial enzyme).