Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Electronic Gene Ontology annotations created by ARBA machine learning models
Cytosolic chaperonin-containing t-complex polypeptide 1 changes the content of a particular subunit species concomitant with substrate binding and folding activities during the cell cycle.
A product of the human gene adjacent to parkin is a component of Lewy bodies and suppresses Pael receptor-induced cell death.
A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity.
Subproteomic analysis of metal-interacting proteins in human B cells.
TCP1 complex is a molecular chaperone in tubulin biogenesis.
Large-scale proteomics and phosphoproteomics of urinary exosomes.
BBS6, BBS10, and BBS12 form a complex with CCT/TRiC family chaperonins and mediate BBSome assembly.
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
Decreased glucocerebrosidase activity in Gaucher disease parallels quantitative enzyme loss due to abnormal interaction with TCP1 and c-Cbl.
PEX14 is required for microtubule-based peroxisome motility in human cells.
Parkin interacts with Ambra1 to induce mitophagy.
Reconstitution of the human chaperonin CCT by co-expression of the eight distinct subunits in mammalian cells.
The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Human TRiC complex purified from HeLa cells contains all eight CCT subunits and is active in vitro.
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
Chaperonin-containing TCP-1 complex directly binds to the cytoplasmic domain of the LOX-1 receptor.
A proteome-scale map of the human interactome network.
Proteostatic control of telomerase function through TRiC-mediated folding of TCAB1.
HtrA3 is a cellular partner of cytoskeleton proteins and TCP1α chaperonin.
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei.
The Chaperonin TRiC/CCT Associates with Prefoldin through a Conserved Electrostatic Interface Essential for Cellular Proteostasis.
Cellular substrates and pro-apoptotic function of the human HtrA4 protease.
Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.
Dlec1 is required for spermatogenesis and male fertility in mice.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
OpenCell: Endogenous tagging for the cartography of human cellular organization.
Multimodal cell maps as a foundation for structural and functional genomics.
Association of CCT/TriC with sphingosine kinase 1
TRiC/CCT binds unfolded G-protein beta subunit
ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT
PDCL binds G-protein beta and TRiC/CCT
ATP binds G-protein beta associated TRiC/CCT
PDCL releases folded G-beta from TRiC/CCT
RGS proteins bind GNB5 and CCT/TRiC
PDCL promotes G-protein beta 5 folding
Release of GNB5:RGS dimers from CCT/TRiC
A gradient of ATP affinities generates an asymmetric power stroke driving the chaperonin TRIC/CCT folding cycle.