Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
Multimodal cell maps as a foundation for structural and functional genomics.
GFPT2/GFAT2 and AMDHD2 act in tandem to control the hexosamine pathway.
Hexosamine biosynthesis in keratinocytes: roles of GFAT and GNPDA enzymes in the maintenance of UDP-GlcNAc content and hyaluronan synthesis.
The murine glutamine:fructose-6-phosphate amidotransferase-encoding cDNA sequence.
Synthesis of UDP-N-acetyl-glucosamine
Annotation inferences using phylogenetic trees
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
Molecular cloning, cDNA sequence, and bacterial expression of human glutamine:fructose-6-phosphate amidotransferase.
O-GlcNAc signaling entrains the circadian clock by inhibiting BMAL1/CLOCK ubiquitination.
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Defective GFPT1 does not transfer an amino group from L-Gln to F6P to form GlcN6P
GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P
A novel variant of glutamine: fructose-6-phosphate amidotransferase-1 (GFAT1) mRNA is selectively expressed in striated muscle.
Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography.
Hexosamine biosynthetic pathway mutations cause neuromuscular transmission defect.
Structural analysis of human glutamine:fructose-6-phosphate amidotransferase, a key regulator in type 2 diabetes.
Initial characterization of the human central proteome.
System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
XBP1(S) activates chaperone genes
Defective GFPT1 causes CMSTA1
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
A probability-based approach for high-throughput protein phosphorylation analysis and site localization.
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
A quantitative atlas of mitotic phosphorylation.
Large-scale proteomics analysis of the human kinome.
Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
Toward a comprehensive characterization of a human cancer cell phosphoproteome.
Loss of GFAT-1 feedback regulation activates the hexosamine pathway that modulates protein homeostasis.
Selected source, assay and cell-context evidence for GFPT1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1