Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Electronic Gene Ontology annotations created by ARBA machine learning models
Role of the multidrug efflux system MexXY in the emergence of moderate resistance to aminoglycosides among Pseudomonas aeruginosa isolates from patients with cystic fibrosis.
MexZ-mediated regulation of mexXY multidrug efflux pump expression in Pseudomonas aeruginosa by binding on the mexZ-mexX intergenic DNA.
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Purified MexZ binds a specific site in the mexZ-mexX intergenic DNA.
"Highly purified MexZ showed direct binding with a specific site of the mexZ-mexX intergenic DNA when probed by a gel retardation assay"
Role of MexZ and PA5471 in transcriptional regulation of mexXY in Pseudomonas aeruginosa.
Crystal structure of MexZ, a key repressor responsible for antibiotic resistance in Pseudomonas aeruginosa.
Antibiotic inducibility of the mexXY multidrug efflux operon of Pseudomonas aeruginosa: involvement of the MexZ anti-repressor ArmZ.
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mexZ deletion raises mexXY expression 5-fold.
"In a mutant strain lacking the mexZ gene encoding a repressor of mexXY gene expression, expression of the efflux operon increases modestly (5-fold)"
Interaction of ArmZ with the DNA-binding domain of MexZ induces expression of mexXY multidrug efflux pump genes and antimicrobial resistance in Pseudomonas aeruginosa.
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ArmZ binds the MexZ N-terminal DNA-binding domain.
"the N-terminal part of MexZ, encompassing the DNA-binding domain, is required for interaction with ArmZ"
mexZ (PA2020) review notes