Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Combined Automated Annotation using Multiple IEA Methods
A variant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of hepatitis C virus.
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IFNL4 was discovered as a novel type III interferon encoded upstream of IFNL3
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A dinucleotide polymorphism (ss469415590 TT/ΔG) determines IFNL4 functionality
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The ΔG allele produces functional IFNL4 protein associated with impaired HCV clearance
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Transient overexpression of IFNL4 induced STAT1 and STAT2 phosphorylation
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IFNL4 induces expression of interferon-stimulated genes (ISGs)
Decoding type I and III interferon signalling during viral infection.
Falcon deep research synthesis for IFNL4