GPKOW source guide

Normal cached texts remain immutable. Access statements below distinguish retained normal caches from independently inspected originals. The evidence JSON preserves exact incoming contexts, partner and construct labels, actual PAINT assertions, and Reactome target paths. A missing current interaction record does not negate an inherited positive annotation.

PMID:16491121

Original source. Original abstract inspected; full Methods uninspected.

The accessible original abstract names T54; detailed assay conditions remain uninspected.

PMID:21044950

The screen uses fluorescence complementation; no target-specific telomeric function is inferred.

PMID:21516116

Study-wide orthogonal validation is not assigned to this individual interaction.

PMID:21880142

Original source. Original XML selected Methods and Results inspected.

Endogenous and expressed GPKOW localize to nuclei in human cells. Overexpression-associated nuclear-envelope accumulation is not assigned as a separate physiological location.

PMID:22365833

Original source. Original publisher PDF pages 9–12 and Fig. 7 inspected; normal cache remains abstract-only.

Fig. 7 tests binding competition, not helicase catalysis.

PMID:25296192

Original source. Original XML selected Methods and Results inspected.

DHX16 binding did not prove obligatory recruitment.

PMID:25416956

Human partners were tested in yeast; literal three-method records are preserved.

PMID:28514442

AP-MS detects co-complex recovery; individual orthogonal validation is not assumed.

PMID:28612833

Original source. Original XML selected family and cellular results inspected.

Carrier-derived lymphoblast clones support aberrant splicing and reduced protein; patient-male cells were unavailable. X-inactivation results varied by tissue and carrier status.

PMID:30021884

The target record specifies unfractionated nuclei; no histone-specific function is inferred.

PMID:31515488

Variant feature metadata remain separate from the incoming unsuffixed product.

PMID:32296183

HuRI records preserve human participants, yeast hosts, fusion tags and tested fragments. Pairwise contacts are retained without assigning partner functions to GPKOW. Current and historical accession/ORF labels remain separate; clone equivalence and pair-specific MAPPIT/GPCA validation are not assumed.

PMID:33509932

Original source. Author original PDF and PDB 7DVQ inspected.

Original Bact preparation precedes branching; GO:0071017 specifies catalytically active B*. Stage nomenclature needs curator clarification.

PMID:33961781

HEK293T and HCT116 records retain their actual experimental contexts.

PMID:39251607

Original source. Original XML selected assay paragraphs inspected.

BioID2 detects neighborhoods of overexpressed fusions in K562 cells.

PMID:40205054

Original source. Original XML and author-linked NDEx network 95bc75d5-d1d1-11ee-8a40-005056ae23aa inspected.

The original network retains exact target edges; AP-MS alone does not establish binary binding.

PMID:40221893

Original source. Indexed official PMC abstract and selected sections inspected; no complete downloaded original or full Methods inspection claimed.

Patient fibroblasts retain variant RNA but show reduced protein. Fly knockout rescue and overexpression comparisons are model-specific; failed humanization does not establish a human developmental activity.

Ontology and source identity

Nucleus decisions use the same located_in context as accepted nucleoplasm localization. The broader term is entailed through part_of; this does not deny the underlying imaging or fractionation results. The two source nuclear extension atoms remain attached to their interaction contexts.

The portable evidence records source identifiers, original line numbers, literal record fields and hashes. Private working paths are omitted. Original paper excerpts are not reproduced in these data joins.

Exact independent evidence locators

The IBA supports cite the original PAINT record, not raw_to_current: JSON pointers /paint_ancestry/assertions/0/literal_ibd (raw 74, stored 0; global GAF line 9013) and /paint_ancestry/assertions/1/literal_ibd (raw 84, stored 84; global GAF line 8560). Both literal assertions are on AN0 / PTN000405990; target AN18 / PTN002496600 and original source hashes are in paint_ancestry.

The minor-complex source defect is independently located at /minor_spliceosome/source_and_term_crossrefs, with the source URL/hash at /minor_spliceosome/source; atomic coverage is at /minor_spliceosome/atomic_coordinates. The added record excerpts come from the retained UniProt CC:SUBUNIT block.

Removing bare GO_REF/sidecar supports from nucleus granularity judgments does not discard their original references. The nucleus criterion compares compatible locations. Distinct major/minor assemblies do not entail identical complex membership.