Source: pre-release post-processed-2026_02_28k.xml, accession O14086. The exact entry is preserved in rpa49-protnlm-source.xml; all original evidence elements and model scores are retained in rpa49-protnlm-source.json. This record is currently Swiss-Prot and is absent from the published 26,856-record TrEMBL pilot list. The current public ProtNLM endpoint returns this record; API availability is distinct from membership in the published pilot list. No training-membership inference is made.
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Original evidence key(s): 1.
| Atomic claim | Assessment | Evidence and limit |
|---|---|---|
| The associated DNA-dependent RNA polymerase transcribes DNA using ribonucleoside triphosphates | CNN at holoenzyme level | The grammatical subject is DNA-dependent RNA polymerase, and Rpa49 is an experimentally established Pol I subunit. The chemistry describes that associated enzyme. The paragraph omits Rpa49’s informative role in maximizing rDNA transcription. |
| Independent Rpa49 polymerase activity | Not asserted; would be incorrect | Rpa49/RPA51 is an accessory A49-family subunit: Pol I lacking it retains nonspecific transcription. No intrinsic RNA-polymerase catalytic center or isolated-subunit synthesis is established. The GO process/complex predictions remain valid because participation in transcription does not require independent catalysis. |
publications/PMID_12893961.md).Family and feature provenance: rpa49-uniprot.txt.