Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on curation of immunofluorescence data
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
CD147 is tightly associated with lactate transporters MCT1 and MCT4 and facilitates their cell surface expression.
The loop between helix 4 and helix 5 in the monocarboxylate transporter MCT1 is important for substrate selection and protein stability.
cDNA cloning of MEV, a mutant protein that facilitates cellular uptake of mevalonate, and identification of the point mutation responsible for its gain of function.
Presence and localization of three lactic acid transporters (MCT1, -2, and -4) in separated human granulocytes, lymphocytes, and monocytes.
Expression and membrane localization of MCT isoforms along the length of the human intestine.
The role of charged residues in the transmembrane helices of monocarboxylate transporter 1 and its ancillary protein basigin in determining plasma membrane expression and catalytic activity.
Subcellular localization of transporters along the rat blood-brain barrier and blood-cerebral-spinal fluid barrier by in vivo biotinylation.
Defining the membrane proteome of NK cells.
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
Quantitative targeted absolute proteomic analysis of transporters, receptors and junction proteins for validation of human cerebral microvascular endothelial cell line hCMEC/D3 as a human blood-brain barrier model.
The centriolar satellite protein SSX2IP promotes centrosome maturation.
Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico.
Functional characterization of 5-oxoproline transport via SLC16A1/MCT1.
Rod-derived cone viability factor promotes cone survival by stimulating aerobic glycolysis.
Establishment and Dysfunction of the Blood-Brain Barrier.
Butyric acid increases transepithelial transport of ferulic acid through upregulation of the monocarboxylate transporters SLC16A1 (MCT1) and SLC16A3 (MCT4).
LC-MS/MS Based Quantitation of ABC and SLC Transporter Proteins in Plasma Membranes of Cultured Primary Human Retinal Pigment Epithelium Cells and Immortalized ARPE19 Cell Line.
Blood-Brain Barrier: From Physiology to Disease and Back.
The circadian clock regulates RPE-mediated lactate transport via SLC16A1 (MCT1).
Quantitative Protein Expression in the Human Retinal Pigment Epithelium: Comparison Between Apical and Basolateral Plasma Membranes With Emphasis on Transporters.
pH-Gated Succinate Secretion Regulates Muscle Remodeling in Response to Exercise.
Quantitative fragmentomics allow affinity mapping of interactomes.
The solute carrier superfamily interactome.
Molecular characterization of a membrane transporter for lactate, pyruvate, and other monocarboxylates: implications for the Cori cycle.
Basigin binds MCT1, MCT3 and MCT4
BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol
BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region
Defective SLC16A1 does not cotransport monocarboxylates, H+ from extracellular region to cytosol
SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol
Physical exercise-induced hypoglycemia caused by failed silencing of monocarboxylate transporter 1 in pancreatic beta cells.