ade3 (SPAC6F12.10c, UniProt O14228) notes

Fetch: correct accession fetched (PUR4_SCHPO, O14228, 1323 aa). Naming trap: S. pombe ade3 = FGAM synthase = ortholog of S. cerevisiae ADE6 (genes/yeast/ADE6); S. cerevisiae ADE3 is C1-tetrahydrofolate synthase. The FLCN paper itself notes PMID:34805795.

Evidence

• PMID:967158 (MF evidence not represented as an experimental GOA row).
• Cytoplasm: GFP library PMID:10759889, ORFeome PMID:16823372; Golgi HDA from ORFeome.
• TORC1: PMID:34805795; vacuole relocalisation on starvation PMID:34805795; authors call it surprising for an enzyme "whose only known activity is in adenine biosynthesis".

Decisions

• Core MF GO:0004642, BP GO:0006189, cytoplasm - consistent with genes/yeast/ADE6.
• Vacuole membrane, Golgi and negative regulation of TORC1 signaling kept non-core (experimental, condition-dependent or mechanistically unresolved).