veA (Aspergillus nidulans) — curation notes
UniProt C8VTV4 (VEA_EMENI). Founding velvet-superfamily member; light-dependent
coordinator of development and secondary metabolism. Velvet tier of the
conidiation_regulatory_cascade module.
- In the dark VeA bridges VelB and LaeA to form the velvet complex. PMID:21152013; PMID:21152013.
- Light-dependent nucleocytoplasmic partitioning (nuclear in dark): many EXP
nucleus/cytoplasm annotations, all ACCEPT.
- Regulation of secondary metabolic process ACCEPT (velvet complex). Regulation of
sulfur metabolic process (IEA/ARBA) kept non-core (unconfirmed for VeA).
- No molecular_function asserted: VeA's characterized role is complex-bridging /
light response rather than a defined enzymatic or DNA-binding activity.
2026-10-01 re-review (GOA refresh)
- Two ARBA IEA rows (GO_REF:0000117) disappeared from the current GOA snapshot and were
marked retired: true (reviews kept): GO:0042762 regulation of sulfur metabolic process
(was KEEP_AS_NON_CORE) and GO:0043455 regulation of secondary metabolic process (was ACCEPT).
Retirement records disappearance from GOA, not a biological judgment.
- Because GO:0043455 is a core process for VeA, added a NEW row (IMP, PMID:18556559, with
PMID:20816830 corroboration) so the core function remains grounded in experimental literature.
- Added verbatim supporting text to the nucleus/cytoplasm EXP rows from PMID:20816830 and
PMID:23341778 (both full text cached).