Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
A human protein-protein interaction network: a resource for annotating the proteome.
Towards a proteome-scale map of the human protein-protein interaction network.
Structure of human ferritin L chain.
Cellular expression, localization and interactions of the product of the human MOST-1 gene associated with breast and prostate cancers.
Interactions between PBEF and oxidative stress proteins--a potential new mechanism underlying PBEF in the pathogenesis of acute lung injury.
Large-scale proteomics and phosphoproteomics of urinary exosomes.
Unraveling of the E-helices and disruption of 4-fold pores are associated with iron mishandling in a mutant ferritin causing neurodegeneration.
Defining the membrane proteome of NK cells.
Mutant ferritin L-chains that cause neurodegeneration act in a dominant-negative manner to reduce ferritin iron incorporation.
Next-generation sequencing to generate interactome datasets.
Development and application of a DNA microarray-based yeast two-hybrid system.
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
Ferritin light chain interacts with PEN-2 and affects γ-secretase activity.
Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo.
A proteome-scale map of the human interactome network.
A massively parallel pipeline to clone DNA variants and examine molecular phenotypes of human disease mutations.
Widespread macromolecular interaction perturbations in human genetic disorders.
NCOA4 Deficiency Impairs Systemic Iron Homeostasis.
Architecture of the human interactome defines protein communities and disease networks.
Ferritin heavy/light chain (FTH1/FTL) expression, serum ferritin levels, and their functional as well as prognostic roles in acute myeloid leukemia.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.
A reference map of the human binary protein interactome.
Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
Structural basis for the intracellular regulation of ferritin degradation.
Multimodal cell maps as a foundation for structural and functional genomics.
Molecular basis for the recently described hereditary hyperferritinemia-cataract syndrome: a mutation in the iron-responsive element of ferritin L-subunit gene (the "Verona mutation").
Mutation in the iron responsive element of the L ferritin mRNA in a family with dominant hyperferritinaemia and cataract.
Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH)
Recruitment Of Cytoplasmic Proteins To Vesicles
Exocytosis of azurophil granule lumen proteins
Structure and expression of ferritin genes in a human promyelocytic cell line that differentiates in vitro.
Cloning of the gene coding for human L apoferritin.
Structural and functional relationships of human ferritin H and L chains deduced from cDNA clones.
Structure of human ferritin light subunit messenger RNA: comparison with heavy subunit message and functional implications.
The amino acid sequence of human liver apoferritin.
Characterization of the human small-ribosomal-subunit proteins by N-terminal and internal sequencing, and mass spectrometry.
Complete sequencing and characterization of 21,243 full-length human cDNAs.
The DNA sequence and biology of human chromosome 19.
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Neuroferritinopathy: missense mutation in FTL causing early-onset bilateral pallidal involvement.
The full-ORF clone resource of the German cDNA Consortium.
A new missense mutation in the L ferritin coding sequence associated with elevated levels of glycosylated ferritin in serum and absence of iron overload.
Initial characterization of the human central proteome.
Human L-ferritin deficiency is characterized by idiopathic generalized seizures and atypical restless leg syndrome.
An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy.
N-terminome analysis of the human mitochondrial proteome.
Scavenging by Class A Receptors
Golgi Associated Vesicle Biogenesis
Iron uptake and transport
FTL original annotation contexts, source scopes and genuine mapping