Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Electronic Gene Ontology annotations created by transferring manual GO annotations between related proteins based on shared sequence features
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.
Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.
Adenosine triphosphate-adenosine-5'-monophosphate phosphotransferase from normal human liver mitochondria. Isolation, chemical properties, and immunochemical comparison with Duchenne dystrophic serum aberrant adenylate kinase.
Cloning and expression of human adenylate kinase 2 isozymes: differential expression of adenylate kinase 1 and 2 in human muscle tissues.
ADP + ADP <=> AMP + ATP [AK2]
AMP + ATP <=> ADP + ADP [AK2]
Interconversion of nucleotide di- and triphosphates
Adenylate kinases 1 and 2 are part of the accessory structures in the mouse sperm flagellum.
Human adenylate kinase 2 deficiency causes a profound hematopoietic defect associated with sensorineural deafness.
Reticular dysgenesis (aleukocytosis) is caused by mutations in the gene encoding mitochondrial adenylate kinase 2.
Failure of metabolic checkpoint control during late-stage granulopoiesis drives neutropenia in reticular dysgenesis.
AK2 activates a novel apoptotic pathway through formation of a complex with FADD and caspase-10.
Release of adenylate kinase 2 from the mitochondrial intermembrane space during apoptosis.
The DUSP26 phosphatase activator adenylate kinase 2 regulates FADD phosphorylation and cell growth.
UniProt P54819 human AK2 record