PMID:10700180
Familial dyserythropoietic anaemia and thrombocytopenia due to an inherited mutation in GATA1.
PMID:11418466
Platelet characteristics in patients with X-linked macrothrombocytopenia because of a novel GATA1 mutation.
PMID:11675338
X-linked thrombocytopenia caused by a novel mutation of GATA-1.
PMID:11861504
Gonadotropins, via cAMP, negatively regulate GATA-1 gene expression in testicular cells.
PMID:12045236
Essential and instructive roles of GATA factors in eosinophil development.
PMID:12200364
X-linked thrombocytopenia with thalassemia from a mutation in the amino finger of GATA-1 affecting DNA binding rather than FOG-1 interaction.
PMID:12483298
Molecular cloning and characterization of the GATA1 cofactor human FOG1 and assessment of its binding to GATA1 proteins carrying D218 substitutions.
PMID:12609092
A novel erythroid differentiation related gene EDRF1 upregulating globin gene expression in HEL cells.
PMID:15701726
Selective impairment of platelet activation to collagen in the absence of GATA1.
PMID:15920471
GATA-1 forms distinct activating and repressive complexes in erythroid cells.
PMID:16783379
An inherited mutation leading to production of only the short isoform of GATA-1 is associated with impaired erythropoiesis.
PMID:17132730
The mediator complex functions as a coactivator for GATA-1 in erythropoiesis via subunit Med1/TRAP220.
PMID:17167422
Hsp70 regulates erythropoiesis by preventing caspase-3-mediated cleavage of GATA-1.
PMID:17420275
GATA-1 and Gfi-1B interplay to regulate Bcl-xL transcription.
PMID:17687519
Thymoquinone suppressses in vitro production of IL-5 and IL-13 by mast cells in response to lipopolysaccharide stimulation.
PMID:18063754
Differential context-dependent effects of friend of GATA-1 (FOG-1) on mast-cell development and differentiation.
PMID:18990226
Temporal and functional profile of the transcriptional regulatory network in the early regenerative response to partial hepatectomy in the rat.
PMID:19411634
GATA-1 associates with and inhibits p53.
PMID:19513100
Direct binding of pRb/E2F-2 to GATA-1 regulates maturation and terminal cell division during erythropoiesis.
PMID:20133935
Developmental silencing of human zeta-globin gene expression is mediated by the transcriptional repressor RREB1.
PMID:22235304
Knockdown of ZNF268, which is transcriptionally downregulated by GATA-1, promotes proliferation of K562 cells.
PMID:22390417
GATA transcription factors are involved in IgE-dependent mast cell degranulation by enhancing the expression of phospholipase C-γ1.
PMID:24245781
CCAR1/CoCoA pair-mediated recruitment of the Mediator defines a novel pathway for GATA1 function.
PMID:2467208
Increased gamma-globin expression in a nondeletion HPFH mediated by an erythroid-specific DNA-binding factor.
PMID:25416956
A proteome-scale map of the human interactome network.
PMID:26019275
A Novel In-Frame Deletion in the Leucine Zipper Domain of C/EBPε Leads to Neutrophil-Specific Granule Deficiency.
PMID:28473536
Impact of cytosine methylation on DNA binding specificities of human transcription factors.
PMID:32911434
A functionally defined high-density NRF2 interactome reveals new conditional regulators of ARE transactivation.
PMID:35030251
Congenital anemia reveals distinct targeting mechanisms for master transcription factor GATA1.
PMID:35512704
Systematic discovery of mutation-directed neo-protein-protein interactions in cancer.
PMID:7678994
Expression of tal-1 and GATA-binding proteins during human hematopoiesis.
PMID:8507862
Expression of mRNA for the GATA-binding proteins in human eosinophils and basophils: potential role in gene transcription.
PMID:8524811
Alternative translation initiation site usage results in two functionally distinct forms of the GATA-1 transcription factor.
PMID:8628290
A palindromic regulatory site within vertebrate GATA-1 promoters requires both zinc fingers of the GATA-1 DNA-binding domain for high-affinity interaction.
PMID:9089398
Conserved structure, regulatory elements, and transcriptional regulation from the GATA-1 gene testis promoter.
GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000052
Gene Ontology annotation based on curation of immunofluorescence data
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
GO_REF:0000113
Gene Ontology annotation of human sequence-specific DNA binding transcription factors (DbTFs) based on the TFClass database
GO_REF:0000117
Electronic Gene Ontology annotations created by ARBA machine learning models
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
Reactome:R-HSA-8935740
RUNX1 and GATA1 bind the promoter of the ITGA2B gene
Reactome:R-HSA-8936481
Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter
Reactome:R-HSA-8936616
RUNX1 and GATA1 bind the promoter of the GP1BA gene
Reactome:R-HSA-8936621
Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter
Reactome:R-HSA-8936979
RUNX1 and GATA1 bind the promoter of the THBS1 gene
Reactome:R-HSA-8937016
Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter
Reactome:R-HSA-8937037
RUNX1 and GATA1 bind the promoter of the MIR27A gene
Reactome:R-HSA-8937050
Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter
Reactome:R-HSA-8956568
RUNX1 binds the core TAL1 complex
Reactome:R-HSA-996755
ZFPM proteins bind GATA proteins
UniProt:P15976
UniProt entry for GATA1 (P15976)
file:human/GATA1/GATA1-external-evidence.md
GATA1 original interaction-table target subsets and construct scope