Gene Ontology annotation through association of InterPro records with GO terms

Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

Annotation inferences using phylogenetic trees

Electronic Gene Ontology annotations created by ARBA machine learning models

Combined Automated Annotation using Multiple IEA Methods

Structural basis and sequence rules for substrate recognition by Tankyrase explain the basis for cherubism disease.

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.

Mammalian Fat and Dachsous cadherins regulate apical membrane organization in the embryonic cerebral cortex.

Structure of the planar cell polarity cadherins Fat4 and Dachsous1.

A synthetic planar cell polarity system reveals localized feedback on Fat4-Ds1 complexes.

Stromal-epithelial crosstalk regulates kidney progenitor cell differentiation.

Amotl1 mediates sequestration of the Hippo effector Yap1 downstream of Fat4 to restrict heart growth.

An evolutionary shift in the regulation of the Hippo pathway between mice and flies.

Giant cadherins Fat and Dachsous self-bend to organize properly spaced intercellular junctions.

Mutations in genes encoding the cadherin receptor-ligand pair DCHS1 and FAT4 disrupt cerebral cortical development.

Role of DE-cadherin in neuroblast proliferation, neural morphogenesis, and axon tract formation in Drosophila larval brain development.

Fat4 intracellular domain controls internalization of Fat4/Dchs1 planar polarity membrane complexes.