Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Electronic Gene Ontology annotations created by transferring manual GO annotations between related proteins based on shared sequence features
Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Combined Automated Annotation using Multiple IEA Methods
The glutathione reductase GSR-1 determines stress tolerance and longevity in Caenorhabditis elegans.
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gst-44 RNAi reduces survival under arsenite stress but not under juglone stress.
"Furthermore, knockdown of an alpha-class related GST (gst-32), an omega-class GST (gst-44) and an extracellular glutathione peroxidase (C11E4.1) less profoundly affected the survival rate under arsenite stress"
Unraveling the functional dynamics of Caenorhabditis elegans stress-responsive omega class GST-44.
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Recombinant GST-44 has DHAR, MMA(V) reductase, thioltransferase and peroxidase activities but no CDNB/ethacrynic acid conjugating activity.
"Furthermore, the enzyme was capable of using GSH as an electron donor to reduce dehydroascorbate (DHA)"
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GST-44::GFP is cytoplasmic in intestine and excretory cell and is induced by arsenic through SKN-1 and PHA-4.
"The upregulation of GST-44 during arsenic stress was"
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gst-44 deletion mutants are short-lived and specifically arsenic-sensitive among the GSTO paralog mutants.
"While the GST‐44 showed a significantly reduced survival rate under arsenic"
Manual literature research for gst-44
WormBase gene description for gst-44 (worm)