PA5484 (KinB, Q9HT87) review notes

No deep-research provider was available. Literature checked: cached PMID:9218420 (abstract only),
PMID:23024348 (full text); Europe PMC search "KinB AND aeruginosa AND phosphatase" (2026-11-05)
found no further biochemical papers. UniProt has no gene name; the protein is KinB in the literature.

Function

Autokinase and AlgB phosphotransferase [PMID:9218420 "COOH-terminal KinB protein was observed to undergo progressive"
autophosphorylation; "rapidly transferred to purified AlgB. Substitutions of the residues conserved"].
Inner-membrane topology with periplasmic N-terminus PMID:9218420.
Phospho-AlgB phosphatase, the dominant in vivo output PMID:23024348. P390S abolishes phosphatase but not autophosphorylation.

PseudoCAP IBA-seed assessment

PTN node	node term	n_seeds	leaf IBAs	seed annotation (term, evidence, PMID)	verdict	rationale	other seeds	IBD stands without this seed?
PTN001293174	GO:0000155 phosphorelay sensor kinase activity	3	30 (13 taxa)	GO:0000155, IDA, PMID:9218420 (PseudoCAP)	SOUND	The abstract reports autophosphorylation of purified KinB and phosphotransfer to AlgB, abolished by substitution of conserved residues. The node term suits a sensor histidine kinase clade.	E. coli EnvZ (P0AEJ4), P. aeruginosa ParS (Q9I2U4)	Yes; EnvZ is a model sensor kinase. No defect.

Other PseudoCAP row: IDA phosphatase activity (PMID:23024348) is sound but general; MODIFY to
GO:0004721 phosphoprotein phosphatase activity (substrate phospho-AlgB). No source defect.

No shared PAINT node with the other genes in this batch or with speE2/np20.