GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000024
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
GO_REF:0000108
Automatic assignment of GO terms using logical inference, based on on inter-ontology links
GO_REF:0000117
Electronic Gene Ontology annotations created by ARBA machine learning models
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
PMID:10604470
Ghrelin is a growth-hormone-releasing acylated peptide from stomach.
PMID:11322507
Growth hormone secretagogue receptor family members and ligands.
PMID:12890514
Growth hormone secretagogue receptors in rat and human gastrointestinal tract and the effects of ghrelin.
PMID:15232612
Ghrelin inhibits leptin- and activation-induced proinflammatory cytokine expression by human monocytes and T cells.
PMID:16511605
Loss of constitutive activity of the growth hormone secretagogue receptor in familial short stature.
PMID:17494105
Facilitation of decidualization by locally produced ghrelin in the human endometrium.
PMID:35027551
Molecular mechanism of agonism and inverse agonism in ghrelin receptor.
PMID:8688086
A receptor in pituitary and hypothalamus that functions in growth hormone release.
Reactome:R-HSA-379048
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11
Reactome:R-HSA-749448
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq
Reactome:R-HSA-749452
The Ligand:GPCR:Gq complex dissociates
file:human/GHSR/GHSR-uniprot.txt
UniProtKB Q92847: human GHSR receptor sequence and curated pharmacology
PMID:42426797
Preliminary investigation of ghrelin in horses and ponies: receptor expression and associations with prandial state, morphometry and signalment.
PMID:25605885
Ghrelin receptor conformational dynamics regulate the transition from a preassembled to an active receptor:Gq complex.
PMID:15070777
Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor.
PMID:12045256
Hypothalamic growth hormone secretagogue receptor regulates growth hormone secretion, feeding, and adiposity.
PMID:16322794
Mice lacking ghrelin receptors resist the development of diet-induced obesity.
PMID:26590421
Hippocampal Dopamine/DRD1 Signaling Dependent on the Ghrelin Receptor.
PMID:40441153
Constitutive ghrelin receptor activity enables reversal of dopamine D2 receptor signaling.
PMID:24367106
Ghrelin triggers the synaptic incorporation of AMPA receptors in the hippocampus.
PMID:26153524
Involvement of PKA and ERK pathways in ghrelin-induced long-lasting potentiation of excitatory synaptic transmission in the CA1 area of rat hippocampus.
PMID:22516464
Ghrelin promotes reorganization of dendritic spines in cultured rat hippocampal slices.
PMID:16873401
Evidence that stimulation of ghrelin receptors in the spinal cord initiates propulsive activity in the colon of the rat.
PMID:15890336
Comparison of the gastroprokinetic effects of ghrelin, GHRP-6 and motilin in rats in vivo and in vitro.
PMID:23525979
Effects of ghrelin on gastric distension sensitive neurons and gastric motility in the lateral septum and arcuate nucleus regulation.
PMID:21778696
GSK1614343, a novel ghrelin receptor antagonist, produces an unexpected increase of food intake and body weight in rodents and dogs.
PMID:17911350
Ghrelin inhibits sympathetic nervous activity in sepsis.
PMID:21642627
Ghrelin modulates physiologic and pathologic retinal angiogenesis through GHSR-1a.
PMID:25337654
Ghrelin protects alveolar macrophages against lipopolysaccharide-induced apoptosis through growth hormone secretagogue receptor 1a-dependent c-Jun N-terminal kinase and Wnt/β-catenin signaling and suppresses lung inflammation.
PMID:19931319
Genetic suppression of ghrelin receptors activates brown adipocyte function and decreases fat storage in rats.
PMID:26512025
Obesity in MENX Rats Is Accompanied by High Circulating Levels of Ghrelin and Improved Insulin Sensitivity.
PMID:19652956
Cognitive enhancing effects of ghrelin receptor agonists.
PMID:39833471
The structure and function of the ghrelin receptor coding for drug actions.
file:human/GHSR/GHSR-deep-research-falcon.md
Falcon deep research report for human GHSR