Gene Ontology annotation through association of InterPro records with GO terms

Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara

Electronic Gene Ontology annotations created by ARBA machine learning models

Combined Automated Annotation using Multiple IEA Methods

Mutations in a human homologue of Drosophila crumbs cause retinitis pigmentosa (RP12).

The Maguk protein, Pals1, functions as an adapter, linking mammalian homologues of Crumbs and Discs Lost.

MPP5 recruits MPP4 to the CRB1 complex in photoreceptors.

FERM protein EPB41L5 is a novel member of the mammalian CRB-MPP5 polarity complex.

The CRB1 Complex: Following the Trail of Crumbs to a Feasible Gene Therapy Strategy.

Structural determinants driving the binding process between PDZ domain of wild type human PALS1 protein and SLiM sequences of SARS-CoV E proteins.

CRB1 has a cytoplasmic domain that is functionally conserved between human and Drosophila.

CRB1 is essential for external limiting membrane integrity and photoreceptor morphogenesis in the mammalian retina.

Crumbs homologue 1 is required for maintenance of photoreceptor cell polarization and adhesion during light exposure.

Pals1/Mpp5 is required for correct localization of Crb1 at the subapical region in polarized Muller glia cells.

A single amino acid substitution (Cys249Trp) in Crb1 causes retinal degeneration and deregulates expression of pituitary tumor transforming gene Pttg1.

Crb apical polarity proteins maintain zebrafish retinal cone mosaics via intercellular binding of their extracellular domains.

The severity of retinal pathology in homozygous Crb1rd8/rd8 mice is dependent on additional genetic factors.

Common and distinctive localization patterns of Crumbs polarity complex proteins in the mammalian eye.

A new CRB1 rat mutation links Müller glial cells to retinal telangiectasia.

Crumbs, the Drosophila homologue of human CRB1/RP12, is essential for photoreceptor morphogenesis.

Correction to: The severity of retinal pathology in homozygous Crb1rd8/rd8 mice is dependent on additional genetic factors.

Comprehensive identification of mRNA isoforms reveals the diversity of neural cell-surface molecules with roles in retinal development and disease.

Human iPSC-Derived Retinas Recapitulate the Fetal CRB1 CRB2 Complex Formation and Demonstrate that Photoreceptors and Müller Glia Are Targets of AAV5.

CRB1-associated retinal degeneration is dependent on bacterial translocation from the gut.

Human CRB1 and CRB2 form homo- and heteromeric protein complexes in the retina.

CRB1 source evidence and product/provenance assessment